BACKGROUND Physical inactivity plays a central role in the age-related decline in muscle strength, an important component in the process leading to disability. Personality, a significant determinant of health behaviors including physical activity, could therefore impact muscle strength throughout adulthood and affect the rate of muscle strength decline with aging. Personality typologies combini...

The shared decline in cognitive abilities, sensory functions (e.g., vision and hearing), and physical health with increasing age is well documented with some research attributing this shared age-related decline to a single common cause (e.g., aging brain). We evaluate the extent to which the common cause hypothesis predicts associations between vision and physical health with social cognition a...

Some of the most serious consequences of aging are its effects on skeletal muscle. The term sarcopenia is widely used to describe the progressive loss of muscle mass and quality with increasing age.1 Sarcopenia is characterized by a gradual decline in strength and a slowing of movement that increases the risk of injury from sudden falls and the need for assistance for the frail elderly to accom...

Our understanding of the molecular and genetic regulation of aging and longevity has been greatly augmented through studies using the small model system, C. elegans. It is important to test whether mutations that result in a longer life span also extend the health span of the organism, rather than simply prolonging an aged state. C. elegans can learn and remember both associated and non-associa...

introduction: andropause is a common clinical entity of advanced age, with a decline in androgen levels in males. many of the signs of male aging are results of this condition with significant decline in their quality of life and adverse effects on multiple organ systems function. androgen deficiency of the aging male (adam) questionnaire is one of the most applied screening tools for androgen ...

Aging is an inescapable fact of human life. In most areas of our lives, aging leads to an unremarkable, gradual decline in physical ability. For example, no one questions why a 40-year-old runner can no longer compete in the Olympics. As the body ages, metabolism slows, joints wear out, and energy is diminished. Aging also has a uniform natural effect on the learning of new skills. As a result,...

Objectives. To investigate whether sensory function declines independently or in parallel with age within a single individual. Methods. Cross-sectional analysis of Baltimore Longitudinal Study of Aging (BLSA) participants who underwent vision (visual acuity threshold), proprioception (ankle joint proprioceptive threshold), vestibular function (cervical vestibular-evoked myogenic potential), hea...

neuropsychological studies have demonstrated that preclinical dementia accompanies a decreasing trend in cognitive state a few years prior to clinical diagnosis. sudden decline in episodic memory and semantic knowledge have been found to have the capability to differentiate patients in preclinical state of dementia from those experiencing normal aging. in addition, decline in episodic memory is...