A 41-year-old male was admitted to the hospital with symptoms of diarrhea, fever and rapidly progressive respiratory distress. A chest radiograph and computed tomography (CT) of the chest and the abdomen showed a large amount of right pleural effusion and a large liver abscess. The patient was thus diagnosed to have amoebic colitis, amoebic liver abscess and amoebic empyema complicated with an ...

The LATIN study (Incidence of aplastic anemia and agranulocytosis in Latin America) is a Latin American multicenter study to estimate the incidence of aplastic anemia and agranulocytosis in Latin America. We now have the results from the Brazilian pilot phase including data from seven centers in the states of Paraná, Goiás, Minas Gerais, Amazonas, Pernambuco and São Paulo. During the pilot stud...

Bone marrow was cultured in vitro for colonies of granulocytes and macrophages five months after a patient had recovered from amodiaquine induced agranulocytosis. The addition of amodiaquine, chloroquine, and sulfadoxine to the culture was followed by a dose dependent inhibition of colony growth in the patient's marrow but not in normal control bone marrow. Colony growth was, however, unaffecte...