Batch and continuous production of the extracellular heme glycoprotein chloroperoxidase (CPO) was studied with an airlift fermentor. We induced Caldariomyces fumago CMI 89362 to form pellets by transferring a small inoculum volume in preculture prior to growth in a 1-liter fermentor. Continuous replacement of the fructose-salts medium (dilution rate, 0.008 h) supported continuous CPO formation ...

For an integrated nitrification-denitrification processes, nitrite formation in the aerobic stage leads to big savings. Recently experimental observations (Garrido et al., 1996) have shown that it is possible to obtain full ammonium conversion with approximately 50 % nitrate and 50 % nitrite in the effluent of a biofilm airlift suspension reactor. With oxygen concentrations between 1 and 2 mg/l...

This research demonstrates the applicability of parallel computing to Air Mobility Command’s aircraft allocation problem. The Tanker Airlift Control Center (TACC) is responsible for worldwide tasking of DoD airlift in a manner that is robust against random future events. Our work seeks to improve this process using a parallel stochastic mathematical program that allocates aircraft to various mi...

The aim of this work is to use optimization as a tool for scale up in airlift bioreactors and apply this approach to a real life process. To put this approach into practice, Chlamydomonas reinhardtii, a green microalgae, was used as a model microorganism. The effects of the design parameters on the performance of the bioreactors were monitored through the changes in mixing and circulation times...

In this article a hydrodynamic and rheological analysis of a continuous airlift bioreactor with high-cell-density system is presented. A highly flocculating recombinant strain of Sacharomyces cerevisiae containing genes for lactose transport (lactose permease) and hydrolysis (beta-galactosidase) was exploited to ferment lactose from cheese whey to ethanol. The magnetic particle-tracer method wa...