Accepted 12 January 1996 In December 1983, a 53-year old Chinese woman presented with a one-year history of generalised pruritus. Various members of her family, extending over four generations, had autoimmunne thyroid disorders. On examination, she had bilateral xanthelasmata but no stigmata of chronic liver disease nor jaundice. Her liver was just palpable but she had neither splenomegaly nor ...

Purpose: The De Ritis ratio (Aspartat transaminase/alanine transaminase) is a critical prognostic factor for some kinds of malignant tumors. Nevertheless, the ratio’s value in preoperative colon cancer staging unclear. purpose this research was to determine and its significance cancer.
 Materials Methods: clinicopathological data 271 individuals with malign were analyzed retrospectively, f...

The hepato-protective effect of Telfaria occidentalis leaves supplementation on paracetamol induced liver toxicity in wistar rats was investigated. A total forty Wistar (female and male) weighing between 150-250g were selected for the study. animals randomly divided into four groups five each. Animals group 1 2 received standard chow only while 3 4 5% 10% T. their feed respectively six weeks. G...

A new method to assay the enzyme, leucine aminopeptidase (LAP; L-leucyl-peptide hydrolase.-3.4.1.1), is described. The technic is an extension of the conventional glutamic-pyruvic transaminase (GPT) reaction. Serum LAP is allowed to react with the substrate L-leucyl-L-alanine to quantitatively generate alanine. This alanine, in the presence of excess -ketoglutaric acid and GPT, rapidly forms py...

BACKGROUND: Dairy cows undergo physiological changes during pregnancy and lactation and cardiovascular system may alter during these periods. OBJECTIVES: Understanding the physiological effects of production periods of dairy cows on heart electrical activities can aid to better monitoring the cardiovascular system in these animals. METHODS: Five multiparous Holstein dairy cows were studied from...

Enzymes are biocatalysts and because of their remarkable properties, they are extensively used in medical diagnosis. Researches in the last two decades have concentrated more on enzymes such as creatine kinase-MB, alanine transaminase, aspartate transaminase, acid phosphatase, alkaline phosphatase etc. for clinical applications. Enzymes are the preferred markers in various disease states such a...

In a study of the composition of the epididymal fluid of rams, attention was given to the fact that nitrogen compounds constitute a great part of the dry matter and that so far seventeen free amino acids have been detected in the fluid (Ch. Neumark, unpublished data). It was therefore deemed of interest to study the enzymes of their metabolism. Two principal transaminases were investigated: glu...

Ethanolic Z. officinale (ZO) extract (200 mg/kg) pretreatment for 20 days in isoproterenol (ISO)-treated rats significantly increased the levels of endogenous myocardial antioxidants (catalase, superoxide dismutase and tissue glutathione), decreased the levels of serum marker enzymes (lactate dehydrogenase, creatine kinase, aspartate transaminase and alanine transaminase) and increased myocardi...