Homozygosity for a large deletion in the solute carrier family 45, member 2 (SLC45A2) gene causes oculocutaneous albinism (OCA) in the Doberman Pinscher breed. An albino Lhasa Apso did not have this g.27141_31223del (CanFam2) deletion in her SLC45A2 sequence. Therefore, SLC45A2 was investigated in this female Lhasa Apso to search for other possible variants that caused her albinism. The albino ...

The visual pathway in albino animals is abnormal in that there is a smaller number of ipsilaterally projecting retinal ganglion cells. There are two possible sites of gene action that could result in such a defect. The first site is the retina where the amount of pigmentation in the retinal pigment epithelium is correlated with the degree of ipsilateral innervation (La Vail et al. (1978) J. Com...

in number (16 of 22) of infants in the dutch laboratory rabbit breeding colony, in aged 45-65 days old, hair loss (alopecia) seen at the top of the head and around a week after the hair fall, was created in a state of complete alopecia. for determination of the cause of hair loss, after the observation and palpation the alopecic area, there have not been any swelling, abscesses, tumors. in s...

The albino visual pathway is abnormal in that many fibres from the temporal retina project to the contralateral visual cortex. The visual projections in a human albino and a control have been investigated with fMRI and VEP during independent visual stimulation of both hemifields. Activity in the occipital cortex in the normal was contralateral to the stimulated visual field, whereas it was cont...

We investigated the possibility of reconstructing light-damaged retinas by photoreceptor transplantation. The outer nuclear layer containing the photoreceptor cells was eliminated in adult albino rat retinas by exposure to constant high-level illumination. Photoreceptors for transplantation were harvested from neonatal rats using a novel isolation technique that maintained the cellular organiza...

Background: Fluoride is present in environment in various forms and ingested by man from solid foods, drinking water and inhaled from the air. Out of these, fluoride is present in large quantities in dissolved state in many sources of drinking water producing toxicity in man. Fluoride can cross the blood-brain barrier and it can cause adverse effects on the brain cell architecture, metabolism, ...

A histochemical staining technique for cholinesterase is reported for the study of corneal nerves in whole-thickness rabbit cornea. The technique is relatively simple, yields reproducible results, allows good definition of the nerve fiber pattern, and provides the investigator, using a binocular microscope, with the advantage of three-dimensional study. When tissue is stained for specific choli...

In Pierrehumbert (1980) three rising accents are posited for English, H*, L+H* and L*+H, but this three-way contrast has often been disputed. In the present experiment, Minnesotan and Southern Californian speakers read two dialogs which included four levels of emphasis. Emphasis lengthened segmental duration, raised the scaling of all tones and delayed H alignment in L+H*. Independently of emph...

the purpose of this study was to look for carbon materials for composting with rabbit manure. rabbit manure was composted with rice straw and mushroom residues. during the composting process, different related parameters were evaluated. results showed that the rabbit manure could be normally co-composted with rice straw or with mushroom residues. the gi value showed that both composts could hel...

Comparisons of the performance curve of a classical conditioning group with the curves of control groups provided unequivocal evidence that elicitation of eyelid responses to the conditioned stimulus was acquired by associations formed between the conditioned stimulus and the unconditioned stimulus.