Objective: To analyze the impact of nigella sativa on Histomorphological changes in doxorubicin treated albino rats.
 Research Design: Experimental research.
 Abode Study: Anatomy Department, BMSI, Karachi, Pakistan.
 Materials and Methods: Piloted 40 rats for 35 days Department BMSI. They were 3-4 months old about 221 to 238 gm weight. Rats separated into 4 groups, Ao, Bo, Co &a...

The effects of Di (2-Ethylhexyl) Phthalate (DEHP) exposure on lipid peroxidation and antioxidant levels in blood samples rats were investigated. Forty female Wistar-Albino weighing 250-300 g used for the study. divided into 5 groups; group 1: control group, 2: positive (corn oil-based diet), 3: 20 mg DEHP per kg body weight (bw) (lowest dose tested), 4: 100 kg/bw (medium 5: 500 (highest tested)...

BACKGROUND As the idea of stem cell technology in the treatment of sensorial hearing loss has emerged over the past decades, the need for in vivo models for related experiments has become explicit. One of the most common experimental models for inner ear stem cell delivery experiments is the Wistar albino rat. AIMS To investigate the surgical anatomy of the temporal bone of the Wistar albino ...

Purpose: To evaluate the effect of vitamin B-complex on the nephrotoxicity of gentamicin in an established rat model. Methods: Adult Swiss albino rats weighing 170±20g were divided into 4 groups of 4 rats each. Each group was given one of the following: placebo injection (Control), 80mg/kg of gentamicin sulphate alone or with 1.5ml/kg/3ml/kg body weight of vitamin B-complex (intramuscular) cont...

PURPOSE To investigate the effect of old age (3 vs. 18 months) on the retinal function of albino (Sprague-Dawley [SD]) and pigmented (Long-Evans [LE]) rats. METHODS Electroretinograms (ERG) were recorded in both albino (SD; 3 months old n = 16, 18 months old n = 16) and pigmented (LE; 3 months n = 16, 18 months n = 5) rats. Data are analyzed for photoreceptor, ON-bipolar, and retinal ganglion...

Background: Thioacetamide (TAA) is a recognized industrial poisonous agent drastically used in animal studies for induction of hepatic necrosis, fibrosis and cirrhosis. It additionally reported to be nephrotoxic through oxidative stress. Quercetin (QE) has high antioxidant capacity via free radical scavenging, transition metal ion binding, lipid peroxidation inhibition. Aim the work: The goal t...

Objects: The phytochemical screening and the antihyperglycemic impact of Pelargonium gravelens were performed to judge ethanol extract using alloxan-induced diabetic rats. Methods: Intragastric ethanolic amount level 220 mg/kg body weight given alloxan-encouraged male albino rats for four weeks. Diabetic control assumed equivalent quantity vehicle (Dimethylsulfoxide, DMSO) processed together wi...

Allium cepa is a popular recipe used traditionally to treat diabetes, cardiovascular diseases, cancer, wounds and infections. The acute sub-acute oral toxicity profile of the aqueous extract peels were evaluated in wistar albino rats order determine its safety for use traditional medicine. median lethal dose (LD 50) body weights food intake determined. peel was carried out accordance with OECD ...

A narcotic or a non-narcotic analgesic that would not cause respiratory depression and addiction in may be used as an alternative to morphine. In Ayurveda a large number of indigenous drugs have been mentioned possessing the analgesic properties e.g Guggul, Erand, Rasna, Bhringaraja, Methika, palandu and prasikayavani. Total alcoholic extracts of Bhringaraja (Eclipta alba) was undertaken to stu...

Glycyrrhiza glabra extract is gaining increasing acceptance as a folk remedy for treatment of wound. We studied the effect of its extract on wound tensile strength in albino rats. 20 male albino rats had a linear 3 cm incision made over skin of back. The animals were randomly divided into two experimental groups, as control and treatment. Animals of control group received topical cold cream onc...