نتایج جستجو برای: alcoholic steatohepatitis
تعداد نتایج: 38571 فیلتر نتایج به سال:
Correspondence to: Professor A M Diehl, Duke University Medical Center, Box 3256, Snyderman/GSRB-1, 595 LaSalle St, Durham, NC 27710, USA; diehl004@ mc.duke.edu _________________________ ‘‘PRIMARY’’ NASH AND THE DYSMETABOLIC SYNDROME Histopathological characteristics distinguish steatohepatitis from other causes of chronic liver injury. For years, the main cause of steatohepatitis was thought t...
INTRODUCTION Nonalcoholic steatohepatitis (NASH), a subset of nonalcoholic fatty liver disease (NAFLD), is becoming an increasing health concern, with current data showing the prevalence in the United States to range between 5.7%–16.5% (1,2). Patients with NASH lack a history of significant alcohol consumption, but liver biopsy findings are almost identical to biopsy findings in patients with a...
In 1980, Ludwig et al. first reported patients of steatohepatitis who lacked a history of excessive alcohol consumption but showed liver histology resembling alcoholic hepatitis and progression to cirrhosis of the liver accompanied by inflammation and fibrosis. The development of nonalcoholic steatohepatitis (NASH) is associated with obesity, diabetes mellitus, insulin resistance, and hyperlipi...
Abstract Non‐alcoholic steatohepatitis (NASH) and alcohol‐associated (ASH) are the major cause of liver‐related mortality with limited therapeutic options available. In this study, we investigated role Src tyrosine kinase in pathogenesis (N)ASH. We examined expression livers from patients NASH, ASH, cirrhosis biliary atresia, preclinical mouse models: methionine choline deficient (MCD)‐diet‐ind...
Non-alcoholic fatty liver disease (NAFLD) represents the most common liver disease in Western countries and often progresses to non-alcoholic steatohepatitis (NASH) leading ultimately to liver fibrosis and liver cancer. The occurrence of hepatocyte cell death-so far characterized as hepatocyte apoptosis-represents a fundamental step from benign steatosis toward progressive steatohepatitis. In c...
The retrospective analysis of 378 medical records inpatients with steatohepatitis (SH) depending on its etiology was performed to identify and study the type anaemic conditions (AC). Among patients SH mixed (including alcoholic) anaemia found in 32.2% cases, alcoholic (ASH) - 36.3%, non-alcoholic (NASH) 22.0 % cases. Macrocytic, hyperchromic prevailed all groups: 47.9%, ASH 56.8%, NASH 71.4%. N...
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