This study investigates the use of microencapsulation by fluidised bed coating for the protection of ascorbic acid during long-term storage under simulated tropical conditions. Microencapsulation materials, loading levels, fluidised bed processing conditions and the results of storage trials were evaluated. Cellets® 350 is a suitable base material, whereas sugar spheres are not suitable due to ...

Multi-competitive enzymatic reactions were performed to determine the selectivity properties of enzymes immobilised in polyacrylamide-alginate (pAAm-Alg) microcapsules. The transesterification of fatty acid ethyl esters of different chain lengths (C2–C14) with various alcohols catalysed by the enzyme lipase Mucor Miehei was chosen as a test system. While the free enzyme exhibited higher selecti...

Microencapsulation as one of the most modern methods has remarkable effects on probiotic survival. In this study Lactobacillus casei (ATCC 39392) and Bifidobacterium bifidum (ATCC 29521) were encapsulated using calcium alginate-gelatinized starch, chitosan coating and inulin via emulsion technique, and were incubated in simulated gastric juice (along with pepsin, pH=1.5) and simulated intestina...

Microencapsulation as one of the most modern methods has remarkable effects on probiotic survival. In this study Lactobacillus casei (ATCC 39392) and Bifidobacterium bifidum (ATCC 29521) were encapsulated using calcium alginate-gelatinized starch, chitosan coating and inulin via emulsion technique, and were incubated in simulated gastric juice (along with pepsin, pH=1.5) and simulated intestina...

Abstract Alginate is a polysaccharide of natural origin, which shows outstanding properties biocompatibility, gel forming ability, non-toxicity, biodegradability and easy to process. Due these excellent alginate, sodium hydrogel form oxidized alginate other based materials are used in various biomedical fields, especially drug delivery, wound healing tissue engineering. can be easily processed ...

This research was done to formulate and assess the sustained release property of metformin tablets prepared from microcapsules produced by ionic gelation technique using Sida acuta gum or sodium carboxymethylcellulose as retardant. isopropyl alcohol precipitation filtrate obtained distilled water maceration powdered dried leaves. Metformin compatibility determined FTIR. were alginate alone with...

Gliclazide (G) is an antidiabetic drug commonly used in type 2 diabetes. It has extrapancreatic hypoglycemic effects, which makes it a good candidate in type 1 diabetes (T1D). In previous studies, we have shown that a gliclazide-bile acid mixture exerted a hypoglycemic effect in a rat model of T1D. We have also shown that a gliclazide-deoxycholic acid (G-DCA) mixture resulted in better G permea...

Poor cell survival and difficulties with visualization of cell delivery are major problems with current cell transplantation methods. To protect cells from early destruction, microencapsulation methods have been developed. The addition of a contrast agent to the microcapsule also could enable tracking by MR, ultrasound, and X-ray imaging. However, determining the cell viability within the micro...