1. (+/-)-2-, (+/-)-3- and 4-tert.-Butylcyclohexanone are reduced in the rabbit to secondary alcohols, which are excreted extensively conjugated with glucuronic acid. 2. The major metabolite of (+/-)-2-tert.-butylcyclohexanone is (+)-cis-2-tert.-butylcyclohexanol, which has been isolated from the urine as [(+)-cis-2-tert.-butylcyclohexyl beta-d-glucosid]uronic acid. The minor metabolite is (+)-t...

A 1,2-cis-alkyl glycosidation protocol that makes use of unprotected phenyl 1-thioglycosyl donors is reported. Glycosylation of various functionalized alcohols was accomplished in moderate to high yield and selectivity to give the 1,2-cis-glycosides. In order to quickly develop optimum glycosylation conditions, an FIA (flow injection analysis)-ESI-TOF-MS method was developed that enabled rapid ...

1,3,5-Trimethyl pyrazolium tetrafluoroborate room-temperature ionic liquid was prepared and employed for the selective oxidation of alkyl/benzyl alcohols using palladium acetate by stirring at room-temperature in presence of air (oxygen from air). This green procedure gave products in moderate to good yields. Moreover, the synthesized 1,3,5trimethylpyrazolium tetrafluoroborate ionic liquid coul...

Little is known about the metabolism in the animal body of monoalkylbenzenes other than toluene and ethylbenzene (cf. Williams, 1947). The information available suggests that the n-alkyl side chains undergo w-oxidation followed by $-oxidation of the terminology (Rules of Carbohydrate Nomenclature, J. chem. Soc., 1952, p. 5108), glucosiduronic acids) andthe alcohols asnon-reducing glucuronides. ...

As a novel Sanger-type reagent, 2-fluoro-5-nitrophenyldiazonium tetrafluoroborate enabled the versatile functionalization of primary and secondary aliphatic alcohols. Based on mild nucleophilic aromatic substitution fluorine atom under unprecedented, base-free conditions, diazonium unit core resulting aryl-alkyl ether could be employed for such diverse transformations as radical C-H activation ...

In this work, vanadium-substituted cesium phosphomolybdate salts with general formulae Cs3+nPMo12−nVnO40 (n = 0, 1, 2, and 3) were synthesized evaluated in the acetalization of benzaldehyde alkyl alcohols. All catalysts characterized through Raman, infrared, ultraviolet–visible spectroscopies, powder X-ray diffraction patterns, isotherms N2 desorption/adsorption, measurements acidity strength. ...

We have found that 0-alkyl bonds in glycerolipids are synthesized by microsomal enzymes of preputial gland tumors when diiydroxyacetone-P or glyceraldehyde-3-P and 1 J4C long chain fatty alcohols are used as substrates; ATP, coenzyme A, and Mg++ are essential cofactors. The 0-alkyl moieties formed from the 1-“Cand 9,10-3H-labeled long chain fatty alcohols show that the fatty alcohol chains are ...

This paper describes the selective reductions with thioborane derivatives, zinc—modified cyanoborohydride, and the ate complex from diisobutylaluminum hydride and n-butyllithium. Reaction of carboxylic acids with 1,3,2-dithiaborinane in the presence of stannous chloride or boron trifluoride etherate in tetrahydrofuran gives 1,3-dithianes in high yields. The reaction of acids with thexylphenylth...

Reductive catalytic fractionation (RCF) is a new class of process that produces mono phenolics close-to-theoretical maximum yield by preserving the biomass polysaccharides as solid residues under hydrogen atmosphere or transfer conditions. Herein, hydrous ruthenium oxide deposited on carbon (HRO@C) and HY-zeolite (HRO@HYZ) catalysts are prepared characterized different analytical techniques (TG...

The catalytic hydrotreatment of humins, the solid byproduct produced from conversion C6 sugars (glucose, fructose) to 5-hydroxymethylfurfural (HMF), using supported Pd@zeolite (Beta, Y, and USY) catalysts with different amounts Pd (i.e., 0.5, 1.0 1.5 wt%) was investigated under molecular hydrogen pressure. highest humins (52.0%) obtained on 1.5Pd@USY catalyst while amount oil (27.3%) in presenc...