The treatment of hair loss diseases is sometimes difficult because of insufficient efficacy and limited options. However, recent advances in understanding of the pathophysiology and development of new remedies have improved the treatment of refractory hair loss conditions. In this article, an update on the management of hair loss diseases is provided, especially focusing on recently reported th...

androgenic alopecia as a physiologic process and benign prostatic hyperplasia (bph) as a pathologic process in the older population are androgen-dependent processes influenced by 5-alpha reductase enzyme which converts testosterone to dihydrotestosterone. this cross sectional study was done to evaluate the relationship between androgenic alopecia and bph. 150 men older than 50 years old, who pr...

Objective: Alopecia areata (AA) is a common, chronic disorder presents as patchy loss of hair on the scalp, beard area, eyebrows and other parts of body. Trichoscopy, dermoscopy of hair, is a non-invasive diagnostic tool which helps in visualization of subsurface features. Diagnosis of AA is easy, however, diffuse alopecia, alopecia on the eyebrows, patients presenting with total loss of hair c...

UNLABELLED BackgroundAcquired alopecia of the lower legs may occur secondary to friction due to socks, footwear, or both on the lower extremities. There is scant literature that reports on this phenomenon.Methods and MaterialsWe describe 5 patients who presented with alopecia of their lower legs induced by socks, footwear, or both. METHODS AND MATERIALS We reviewed PubMed for the following te...

Alopecia areata incognita, also known as diffuse alopecia areata, is a rare form of alopecia areata described predominantly in young women. In cases of alopecia areata incognita, the typical patchy distribution of hair loss in classical alopecia areata is absent, but abrupt and intense hair loss is characteristic. While the clinical picture presented by this disease closely resembles that of te...

biotin is a water-soluble vitamin and co-factor for activation of carboxylases apoenzymes. biotinidase enzyme is essential for release of biotin from apoenzymes. absence of biotinidase is an autosomal recessive trait with a prevalence of 1 in 60000. clinical manifestations of biotinidase deficiency include dermatitis, alopecia, seizures, hypotonia, developmental delay, hearing loss, visual impa...

Background Histopathological study of alopecia generally requires both vertical and transverse sections (VS and TS) and this may demand the need for multiple scalp biopsy samples. Here, we suggest a new processing technique which provides both VS and TS from a single biopsy, thus making the interpretation easier. Materials and Methods All formalin-fixed scalp biopsy specimens were processed r...

BACKGROUND Telogen effluvium (TE) is a type of acquired, diffuse alopecia that occurs due to an abnormal shift of scalp hair follicles from anagen to telogen, leading to premature shedding of hair. Previous studies have suggested the existence of a neuroimmunologic "brain-hair follicle" axis, in which mast cells have been implicated as an important link between the nervous system and immunologi...

we present a 21-years old woman with alopecia universalis, generalized vitiligo, and graves' disease. she had had thyroidectomy in early childhood and was receiving replacement therapy with levothyroxine. the patient was treated with systemic puva and glucocorticoid in combination with topical treatment for alopecia. after 6 months of treatment, alopecia was reversed but vitiligo was unchanged.

Prostaglandin F2α analogs, commonly prescribed for glaucoma treatment, have been shown to induce side effects such as cutaneous hypertrichosis and hyperpigmentation. Therefore, these medications have theoretic applications in the treatment of alopecia and disorders of hypopigmentation. We reviewed the literature to find original studies assessing the use of prostaglandin F2α analogs in these se...