Alfa-cypermethrin (α-CP) a synthetic pyrethroid (type-II) insecticide, dissolved in dimethyl sulfoxide (DMSO-1 mL) was given consecutive daily orally for 60 days at 1/10 LD50 (14.5 mg/kg). The animals were sacrificed on day 61. Biochemicals, cytochrome P450, b5 contents in liver along with antioxidant status, tissue residual concentration, and brain GABA level were studied. It increased the ser...

The aim of study was to evaluate the effect of atrazine exposure (5, 15, 20, and 30 mg·L(-1)) on common carp and the ability of regeneration. During 96 h exposure we observed abnormal behavior in fish exposed to 20 and 30 mg·L(-1). Mortality and histological alterations were noticed only in the group exposed to 30 mg·L(-1). Most experimental groups showed significantly (P < 0.05) lower values o...

background: faba bean (vicia faba) is a rich source of protein and carbohydrates that is used as a vegetable ingredient in diet of livestock, poultry and fish, in many countries. objectives: this study was conducted to assess the effects of different levels of faba bean on the serum lipid levels and liver function of farmed beluga sturgeon (huso huso). methods: 144 juvenile beluga (82.38 ± 0.83...

Aims: Both ischemia and reperfusion (IR) can cause damages in cells. There are several studies to eliminate the damage. Tirofiban Hydrochloride (TH) is a common glycoprotein IIb/IIIa inhibitor and is being used for ischemic disorders for many years. We aimed to determine the therapeutic effects of tirofiban in liver ischemia reperfusion injury model in this animal study. Materials and methods: ...

background &amp; aim: marshmallow (althaea officinalis) is one of the most popular medicinal plants used in traditional medicine with antibacterial and antioxidant properties. this study was conducted to evaluate the effects of marshmallow extract (althaea officinalis l.) administration on blood cells and biochemical parameters of carp liver. experimental: 150 carp (weighing 37.65 ± 4.40 g) wer...

BACKGROUND To evaluate the effect of continuous, moderate-intensity ultra-endurance running exercise on skeletal muscle and hepatic damage, as indicated by serum enzyme activity measured immediately following the race. METHODS Thirty-nine runners of the Spartathlon race (a 246-km continuous race from Athens to Sparta, Greece) who managed to complete the race within the 36-h limit participated...

conclusions in conclusion, we have shown that vitamin c administration provides protection against csa-induced injury in rat liver function and may have hepatoprotective role in the patients experiencing csa treatment. background cyclosporine a (csa) is an important immunosuppressive agent; however, its clinical use is limited by several side effects such as hepatotoxicity. vitamin c (ascorbic ...

Background: Paraquat is a non-selective contact herbicide, widely used to control weeds in agriculture farms and aquatic plants in surface waters. Paraquat can have adverse effects on the health of aquatic organisms. The aim of this study was to detect the alterations in the blood biochemical parameters of common carp exposed to sub-lethal concentrations of commercial formulations of paraquat. ...