Models of amino acid substitution present challenges beyond those often faced with the analysis of DNA sequences. The alignments of amino acid sequences are often small, whereas the number of parameters to be estimated is potentially large when compared with the number of free parameters for nucleotide substitution models. Most approaches to the analysis of amino acid alignments have focused on...

Models of amino acid substitution present challenges beyond those often faced with the analysis of DNA sequences. The alignments of amino acid sequences are often small, whereas the number of parameters to be estimated is potentially large when compared with the number of free parameters for nucleotide substitution models. Most approaches to the analysis of amino acid alignments have focused on...

We have determined the nucleotide sequence of the yeast ILV2 gene which codes for the amino acid biosynthetic enzyme acetolactate synthase (ALS). ALS has recently been shown to be the target in bacteria, yeast and plants, of the potent new herbicide sulfometuron methyl. The coding sequence for the ILV2 polypeptide contains 2061 base pairs. Comparison of deduced amino acid sequences indicates co...

【Abstract】We describe a new approach to clustering of amino acid sequences using K-Medoids Method. This method combines K-Medoids method, Dynamic Programming and other new theories in Biology. Experiments have proved that our method can get satisfying results. We believe that the method we proposed in this paper is a powerful and flexible tool for clustering of amino acid sequences. 【Keywords】C...

DNA sequences of single-copy genes coding for chitin synthases (UDP-N-acetyl-D-glucosamine:chitin 4-beta-N-acetylglucosaminyltransferase; EC 2.4.1.16) were used to characterize ectomycorrhizal fungi. Degenerate primers deduced from short, completely conserved amino acid stretches flanking a region of about 200 amino acids of zymogenic chitin synthases allowed the amplification of DNA fragments ...

the objective of this research is to identify arabidopsis thaliana genes encoding acid phosphatases induced by phosphate starvation. multiple alignments of eukaryotic acid phosphatase amino acid sequences led to the classification of these proteins into four groups including purple acid phosphatases (paps). specific primers were degenerated and designed based on conserved sequences of paps isol...

Comparison between two amino-acid-sequences was quantified by matrices. The hydrophilicity of each amino acid was used as a parameter to characterize the sequence and its functional aspect in a water environment. The eigenvalues calculated in the linear transformation give an image of a biochemical conversion between two amino-acid-sequences.