background :cytotoxic t lymphocyte-associated antigen-4 (ctla-4) is an important negative regulator of t-cell responses. the -1722tc polymorphism of the ctla-4 gene may be associated with systemic lupus erythematosus (sle) risk, but related results from previous studies have been inconsistent. we carried out a meta-analysis to assess this association more precisely.   methods : a systematic sea...

conclusions the majority of iranian women had neutral attitudes towards menopause, which may be evidence of poor knowledge about menopause. therefore, it is suggested that appropriate educational programs be developed and implemented by policymakers in order to increase knowledge and raise awareness among women about menopause. results out of the 21 selected documents, 11 studies were eligible ...

introduction: the aim of the present research was to conduct a meta-analysis on the effectiveness of play therapy studies on behavioral disorders in children. method: the method of this study was meta-analysis. twenty two studies from throughout iran (1996 to 2012) including 637 participants were used in this meta-analysis. data was analyzed using standardized mean difference effect size method...

background: gastric cancer is the second most common cause of death from cancer. as conflicting studies have recently been published, we aimed to evaluate the magnitude of the epidemiological evidence for an association between alcohol consumption and gastric cancer. methods: this study is a meta-analysis of case-control studies which have been performed during 1989 to 2007. we systematically r...

conclusions in total, iran was classified within the low–intermediate hbv prevalence areas (2% - 4%), while according to recent data (after 2010), iran was classified within the low hbv prevalence areas (< 2%), indicating that preventive measures conducted in iran have been effective. results the polled estimated prevalence of hbv infection in the general population of iran was 2.2 % (95% ci: 1...

background: students' view is an important factor in assessing the quality of universities. servqual pattern is regarded as the most prominent for services quality measurement. this study aimed to review systematically studies that investigated the quality of educational services. methods: a systematic review and meta-analysis of studies evaluating students’ viewpoint about quality of education...

background: there is a great deal of descriptive studies on obesity in iran, mostly assessed the prevalence and its relation­ship with various risk factors and chronic diseases. in order to obtain/give a better insight into the epidemiology of obesity in iran in recent years and assess its heterogeneity around the country, we reviewed systematically all available studies and ana­lyzed their fin...

background: to investigate the relation between serum leptin levels and cerebral infarction (ci) by meta-analysis. materials and methods: scientific literature databases were searched for studies published in chinese and english. after retrieving relevant articles through database searches and screening using predefined selection criteria, high-quality studies related to our research topic were...

how to cite this article: babaknejad n, sayehmiri f, sayehmiri k, mohamadkhani a, bahrami s. the relationship between zinc levels and autism: systematic review and meta-analysis. iran j child neurol. autumn 2016; 10(4):1-9.   abstract objective autism is a complex behaviorally defined disorder. there is a relationship between zinc (zn) levels in autistic patients and development of pathogenesis...