Conventional devices used for surgically assisted rapid palatal expansion are tooth-borne. Dental fixation entails a number of possible drawbacks such as loss of anchorage, skeletal relapse during and after the expansion period, cortical fenestration and buccal root resorption. A bone-borne titanium device with interchangeable expansion modules, used with a callous distraction policy, is presen...

Maintaining torque with sliding mechanics in maxillary anterior teeth especially presence of large extraction spaces has become a major concern among orthodontist. Loss occurs owing to play between bracket system and arch wires. Thus, for control various wire twisting torquing axillaries have been introduced. Not only do these techniques cause certain discomfort patients but also extends patien...

The iPanda is fabricated on the patient’s working cast. An .035" round stainless steel wire is bent with a Young plier to produce a 12mm-long, 2mm-wide loop, which is then customized to create a self-locking system between the iPanda and the midpalatal miniscrew heads. This system allows easy and quick connection to and removal from the miniscrews without the need for ligatures or composite mat...

The hair follicle (HF) undergoes cycles of growth (anagen), regression (catagen) and rest (telogen) phases. Both chronic reactive loss are linked to a dysfunction the HF cycle leading premature loss. Therefore, use specific active ingredients targeting could improve aim this study was evaluate efficacy 3 on anchorage in dermal papilla cells isolated from human (DPC): new patented extract Silybu...

Anchorage-independent growth is a hallmark of oncogenic transformation. We reported that the mitogen-activated protein/extracellular signal-regulated kinase kinase (MEK) inhibitor U0126 inhibited anchorage-independent growth of Ki-ras-transformed rat fibroblasts by simultaneously blocking both extracellular signal-regulated kinase (ERK) and mammalian target of rapamycin (mTOR)-p70(S6K) pathways...

PURPOSE The aim of this study was to assess dental anchorage qualities when the pendulum appliance is used for distal molar movement. MATERIAL Thirty adolescents in various dentition stages received a modified pendulum appliance with a distal screw and a specially preactivated pendulum spring for bilateral molar distalization in the maxilla. The subjects were subcategorized into 3 groups of 1...

A novel breast cancer cell line (RAO-3) was established by transduction of the Q61L mutant RAS into human mammary epithelial cells that were immortalized with catalytic subunit of telomerase (hTERT). The cells displayed anchorage-independent growth and proliferation, and formed human mammary spindle cell carcinoma when injected into nude mice. Chromosome locus 1q22-23 was partially duplicated a...