The effects of three premedication regimens were compared in 45 healthy patients in whom anaesthesia was induced with diprivan 2 mgkg" I.V Premedication with diazepam 10 mg orally and droperidol 2.5-5 Omg and piritramide 7.5-15.0 mg i.m. resulted in less pain on injection and a more profound sleep from dipnvan than premedicanon with diazepam 10 mg orally or no premedication. No differences in s...

Nitric oxide (NO) has been implicated in large number of pathologies ad in normal physiological function of the brain. The aim of this study was to recognize the effect of Nitro-L-Arginine Methyl Ester mHC1 (NAME) and L-Arginine Ethyl Ester.HC1 (ARGININE) on reactivity of the central DA Dg receptor to agonist (Quinpirole) in rats. For this reason we have been used specific behavioural procedure...

Medicinal plants may provide valuable therapeutic agents in modern medicine and traditional system, especially areas where the drugs are unavailable, expensive or predispose to life threatening complications. One of these is Garlic (Allium L. liliaceae) which used as foodstuff, condiment, flavoring folk medicine. The aim this study was investigate effect garlic juice on plasma glucose concentra...

Abstract Nickel is a heavy metal distributed ubiquitously in nature. It accumulates in soil as a result of human activities, including mining and industries development. It may be poisonous to plants, humans, animals and microorganisms. The present study was implemented as a factorial experiment with a Randomized Complete Block Design (RCBD), of three replications in calcareous soils of Karaj...

Channel catfish Ictalurus punctatus fingerlings were fed purified diets supplemented with iron at levels of 0, 20, 60, and 180 mgkg from iron sulfate (FeS) or 5, 10, 20, 60, and 180 mgkg from iron methionine (FeM) in triplicate tanks for 8 wk. Fish were then divided into two groups and subjected to different assays to measure disease resistance and individual immune functions. Representative fi...

A percepção dolorosa, avaliada funcionalmente através do sistema analgésico endógeno, reflete a atividade nociceptivo, o qual depende nível de excitabilidade nervoso, portanto, procura vias e formas que reduzam deste tornou-se uma preocupação humana para assim aliviar da dor. Objetivo: Determinar limiar excitação nociceptivo em animais (camundongos) submetidos tratamento com diferentes doses cl...

The objective of this study is to investigate the effect of breastfeeding on childhood obesity in China.We used data collected from the China Family Panel Studies, an ongoing, prospective, and nationwide longitudinal study to explore the extensive and dynamic social changes in China. A total of 7967 children were included in the analysis. Duration of breastfeeding was first treated as a continu...

For warm-blooded species, the hazardous dose of a chemical (HD50) is an upcoming and important characteristic in the assessment of toxic chemicals. Generally, experimental information is available for a limited number of warm-blooded species only, which causes statistical uncertainty. Furthermore, when small datasets contain an unrepresentative sample of species, they can cause systematic uncer...

Schizophrenia presents a substantial clinical and economic burden to the health-care system. In QUAlity of LIfe with AbiliFY Maintena (QUALIFY), a randomized head-to-head study of aripiprazole once-monthly 400 mg (AOM 400) compared with paliperidone palmitate (PP; 78-234 mg/mo), AOM 400 demonstrated greater improvement in health-related quality of life and functioning in patients with stable sc...

Animal work on the behavioral effects of antipsychotic treatment suggests that different dosing regimens could affect drug sensitivity differently, with an intermittent treatment regimen tending to cause a sensitization effect, while a continuous treatment causing a tolerance. In this study, we explored how haloperidol (HAL) sensitization induced throughout adolescence and tested in adulthood w...