The Saint-Lazare Hospital and its annexes are situated near the Gare de l'Est, more or less on the site of the old prison of Saint-Lazare which used to occupy number 107, Faubourg Saint-Denis. The buildings stretch from Faubourg Saint-Denis as far as La Cour de la Ferme Saint-Lazare. The front entrance is at 9, Cour de la Ferme Saint-Lazare. It is a magnificent modem building, built and planned...

The WHO biowaiver procedure for BCS Class II weak acids was evaluated by running two multisource IR ibuprofen drug products (Ibuprofen, 200 mg tablets, Tatchempharmpreparaty, Russia and Ibuprofen, 200 mg tablets, Biosintez, Russia) with current Marketing Authorizations (i.e. in vivo bioequivalent) through that procedure. Risks associated with excipients interaction and therapeutic index were co...

1 Regulation 6 of the Genetically Modified Organisms (Contained Use) Regulations 2000, GMO(CU), requires that a suitable and sufficient assessment of the risks to human health and the environment be carried out before any activity involving genetic modification of micro-organisms is commenced. The assessment must take into account the matters in Part I of Schedule 3 and include the steps in Par...

This report presents the recommendations of the WHO Expert Committee responsible for updating the WHO Model Lists of Essential Medicines. It contains a summary of the Committee's considerations and justifications for additions and changes to the Model Lists, including its recommendations. Annexes to the main report include the revised version of the WHO Model List of Essential Medicines (17th e...

Design aids in the form of load tables or span are well known to engineers and commonly used timber steel design. Such reduce need for repetitive calculation allow easy ‘what-if’ queries during They also permit rapid communication minimum design requirements. This paper demonstrates an approach developing full culm bamboo elements compression flexure. The based on provisions ISO 22156:2021 most...

Afin d’appréhender les mécanismes qui sous-tendent la physiologie de la vision, la connaissance des bases embryologiques du développement de l’œil et de ses annexes est un prérequis indispensable. La morphogénèse oculaire débute au cours de la quatrième semaine de vie embryonnaire, alors que l’ébauche oculaire s’individualise des diverticules latéraux du cerveau antérieur par des mouvements mor...

Nous rapportons le cas d'une patiente âgée de 25 ans, primigeste primipare, sous contraceptif oral depuis 5 ans arrêté 3 mois avant la grossesse. La patiente n'a jamais été suivie pour sa grossesse. A l'admission de la patiente, l'examen a objectivé une hauteur utérine à 30 cm, bruits cardio-foetaux bien perçus. Au toucher vaginal, le col parait effacé à 90% et dilaté à 3 cm. La présentation es...

The purpose of standardisation of the ergonomic assessment of speech communications is to assure a certain level of speech communication quality for various applications. The quality of speech communications is assessed in case of warning, danger, or information messages for work places, public areas, meeting rooms, and auditoria. In many applications direct communication between humans is cons...