نتایج جستجو برای: anti apoptosis
تعداد نتایج: 499589 فیلتر نتایج به سال:
Today, plant compounds and substances of natural origin as bio products are strongly recommended for the prevention treatment cancer. In field biomedicine anti-viral, anti-inflammatory, anti-oxidant properties among most known activities Humus obtained from humus. this study, effect humic fulvic acids (HA, FA), product humus, on breast cancer cells (MCF7), common women, was investigated. To ach...
Prolonged (>24 h) exposure to anti-IgM (an antigen surrogate that induces membrane cross-linking and apoptosis) induced a 3-fold increase in the mass of endogenous ceramide measured by 32P labeling by diacylglycerol kinase and a 4-fold increase in ceramide as measured by metabolic labeling with [3H]palmitate in a B-lymphocyte cell line, WEHI 231. This correlated with the induction of apoptosis....
Apoptosis (programmed cell death) of T lymphocytes has been proposed as a mechanism which plays an important role in the pathogenesis of human immunodeficiency virus (HIV) disease. Activation of Fas (CD95) can either result in costimulation of proliferation and cytokine production or in the induction of apoptosis of T lymphocytes. This raises the possibility that Fas is involved in the observed...
Synergistic Effects of Arsenic Trioxide and Radiation: Triggering the Intrinsic Pathway of Apoptosis
Background: Arsenic trioxide (ATO) has been reported as an effective anti-cancer and a US Food and Drug Administration (FDA) approved drug for treatment of some cancers. The aim of this study is to determine the underlying apoptosis molecular and cellular mechanisms of ATO in the presence or absence of ionizing radiation (IR) in vitro in the glioblastoma multiforme (GBM) cell line, U87MG. Metho...
Both extracellular signal-regulated kinase (ERK) and c-Jun NH2-terminal kinase (JNK) have been implicated in mediating the signaling events that precede apoptosis. We studied the activation of these kinases during apoptosis of WEHI 231 B cells. Surface IgM ligation induces apoptosis of WEHI 231 cells. This effect is augmented by simultaneous engagement of CD95 and is inhibited by costimulation ...
Introduction: It was reported that morphine could induce apoptosis in neurons. However, its specific mechanistic pathways remain elusive. The present study was undertaken to determine whether morphine could induce apoptosis in PC12 cells, a neuronal cell line, and the involvement of Bax and Bcl-2, as upstream factors of mitochondrial pathway. Methods: In an experimental study, the viabili...
rheum turkestanicum janischew. (polygonaceae) is a plant that grows in central asia and in north-east of iran. traditionally, people use roots of r. turkestanicum as an anti-diabetic and anti-hypertensive as well as anticancer agent. in this study the cytotoxicity and apoptogenic properties of ethyl acetate (etoac), n-hexane and h2o extracts from rheum turkestanicum janischew. (polygonaceae) ro...
Tamoxifen is routinely used for treatment of Estrogen-positive breast carcinoma. Approximately, 50% of patients with metastatic cancer will develop resistance to Tamoxifen. In this research, Tamoxifen was combined with the anti-cancer compound Curcumin. Diblock nanopolymer was used to package the new formulation of Curcumin and Tamoxifen. Anti-cancer efficacy of the obtained compound was evalua...
در این برنامه 229 نفر از افراد زیر 30 سال در زابل انتخاب شدند و نمونه خون جهت بررسی igg anti hav گرفته شد و جهت انجام آزمایش نمونه ها با حفظ زنجیره سرما به سازمان انتقال خون زاهدان فرستاده شد. در این بررسی از 229 نفر 117 نفر مونث (51/1 درصد) و 112 نفر مذکر (48/9 درصد) بودند. از کل جمعیت 203 نفر از نظر igg anti hav مثبت بودند (88/6 درصد) و 26 نفر igg anti hav در آنها منفی بود. فراوانی عفونت hav ...
We have previously shown that injection of anti-glycoprotein (GP) IIb induces murine immune thrombocytopenia (ITP) and that intravenous immunoglobulin (IVIg) ameliorates ITP. We hypothesise that murine ITP may be associated with platelet apoptosis, which is upregulated by anti-GPIIb and downregulated by IVIg. The current study demonstrated that anti-GPIIb injection induced three critical apopto...
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