نتایج جستجو برای: antibacterial mechanism

تعداد نتایج: 604106  

Journal: :Antimicrobial agents and chemotherapy 2006
Katherine Young Hiranthi Jayasuriya John G Ondeyka Kithsiri Herath Chaowei Zhang Srinivas Kodali Andrew Galgoci Ronald Painter Vickie Brown-Driver Robert Yamamoto Lynn L Silver Yingcong Zheng Judith I Ventura Janet Sigmund Sookhee Ha Angela Basilio Francisca Vicente José Rubén Tormo Fernando Pelaez Phil Youngman Doris Cully John F Barrett Dennis Schmatz Sheo B Singh Jun Wang

Condensing enzymes are essential in type II fatty acid synthesis and are promising targets for antibacterial drug discovery. Recently, a new approach using a xylose-inducible plasmid to express antisense RNA in Staphylococcus aureus has been described; however, the actual mechanism was not delineated. In this paper, the mechanism of decreased target protein production by expression of antisense...

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