Introduction: Resistance of pathogenic organisms to countenance antibiotics has become a worldwide problem with serious consequences on the treatment of infectious diseases. The aim of this study was to evaluate antibiotic resistance and also the detection of transferred antibiotic resistance by plasmid in clinical Proteus isolates. Materials and methods: A total of 250 urine samples were ...

The results of a series of antibiotic resistance tests on 118 strains of Staphylococcus aureus isolated from patients attending a casualty department are recorded. Forty-six per cent. of the strains were resistant to penicillin, 12% to streptomycin, 7.5% to tetracycline, and small numbers to the other antibiotics. It is suggested that tetracycline should be used in those infections which are su...

Nonribosomal peptide antibiotics, including polymyxin, vancomycin, and teixobactin, most of which contain D-amino acids, are highly effective against multidrug-resistant bacteria. However, overusing antibiotics while ignoring the risk of resistance arising has inexorably led to widespread emergence of resistant bacteria. Therefore, elucidation of the emerging mechanisms of resistance to nonribo...

introduction: drug resistant staphylococci are the most important agents of nosocomial infections. in this survey, effect of different antibiotics on these bacteria and their drug resistance was investigated. methods: the study included 500 strains of staphylococci. minimum inhibitory concentrations of all antibiotics was determined by the broth macro dilution technique and standard methods fro...

Colistin relates to the polymyxin group of antibiotics. This antibiotic is still used to destroy gram-negative bacteria as a last resort. However, resistance to this antibiotic has been reported and is appearing day by day. Not much information is available on the exact mechanisms of resistance to this antibiotic. Also, not enough information about pharmacokinetics and pharmacodynamics is avail...

The rapid development of resistance in bacteria is an evolutionary response to the selective pressure of antibiotics and results from natural selection. It is established that microbial adaptation evolves, and the cause for the development of antibiotic resistance is the widespread misuse of antibiotics. Pollution of the environment by antibiotic resistance genes can increase the chances of hum...

Antibiotics resistance is a serious biomedical issue as formally susceptible organisms gain resistance under its selective pressure. There have been contradictory results regarding the prevalence of resistance following withdrawal and disuse of the specific antibiotics. Here, we use experimental evolution in "digital organisms" to examine the rate of gain and loss of resistance under the assump...

Antibiotic resistance is a global challenge that impacts all pharmaceutically used antibiotics. The origin of the genes associated with this resistance is of significant importance to our understanding of the evolution and dissemination of antibiotic resistance in pathogens. A growing body of evidence implicates environmental organisms as reservoirs of these resistance genes; however, the role ...

introduction: resistance of pathogenic organisms to countenance antibiotics has become a worldwide problem with serious consequences on the treatment of infectious diseases. the aim of this study was to evaluate antibiotic resistance and also the detection of transferred antibiotic resistance by plasmid in clinical proteus isolates. materials and methods: a total of 250 urine samples were colle...