نتایج جستجو برای: antiemetics

تعداد نتایج: 1498  

Background: Nausea and vomiting are among the most important side-effects associated with chemotherapy in children with cancer, affecting the quality of their lives. Clinical guidelines for selecting antiemetics are effective in reducing acute chemotherapy-induced nausea and vomiting (CINV). Materials and Methods: The present quasi-experimental study compared the effectiveness of the Pediatric...

2016
Megan Brafford May Ashley E Glode

Chemotherapy-induced nausea and vomiting (CINV) is one of the most common symptoms feared by patients, but may be prevented or lessened with appropriate medications. Several antiemetic options exist to manage CINV. Corticosteroids, serotonin receptor antagonists, and neurokinin receptor antagonists are the classes most commonly used in the prevention of CINV. There are many alternative drug cla...

Journal: :American family physician 2012
William E Cayley

www.aafp.org/afp Volume 85, Number 11 ◆ June 1, 2012 Clinical Scenario A five-year-old girl is brought to your clinic by her parents. She has had nausea and vomiting for the past two days, has been unable to keep fluids down, and appears dehydrated. The parents would like to avoid hospitalization, if possible, and are wondering if any medications are safe and effective for controlling her sympt...

Journal: :American family physician 2015
Zachary A Flake Becky S Linn Jaime R Hornecker

Nausea and vomiting are mediated primarily by three neurotransmitter pathways: visceral stimulation releases dopamine and serotonin; vestibular and central nervous system activation release histamine and acetylcholine; and chemoreceptor trigger zone activation releases dopamine and serotonin. Clinicians can improve the effectiveness and cost-effectiveness of treatments by targeting the appropri...

2015
Lauren A. Trepanier

The first step before considering an antiemetic in a dog or cat is a reasonable work-up to rule out serious underlying disease. Every acutely vomiting animal that is brought to a veterinary clinic deserves two view abdominal radiographs to rule out obstruction. Using antiemetics empirically in animals with unrecognized GI obstruction can delay the diagnosis and worsen the prognosis. If vomiting...

Journal: :Journal of oncology practice 2011
Ethan Basch Ann Alexis Prestrud Paul J Hesketh Mark G Kris Petra C Feyer Mark R Somerfield Maurice Chesney Rebecca Anne Clark-Snow Anne Marie Flaherty Barbara Freundlich Gary Morrow Kamakshi V Rao Rowena N Schwartz Gary H Lyman

PURPOSE To update the American Society of Clinical Oncology (ASCO) guideline for antiemetics in oncology. METHODS A systematic review of the medical literature was completed to inform this update. MEDLINE, the Cochrane Collaboration Library, and meeting materials from ASCO and the Multinational Association for Supportive Care in Cancer were all searched. Primary outcomes of interest were comp...

Journal: :Annals of palliative medicine 2012
Howard S Smith Lorraine R Cox Eric J Smith

It is well appreciated that a number of things (e.g., various insults, chemotherapeutic agents, radiation) may lead to the release of serotonin from the enterochromaffin of the gastrointestinal tract. Released serotonin may then bind to certain 5-HT3 receptors and promote nausea/vomiting. 5-HT3 receptor antagonists may ameliorate nausea/vomiting in a number of circumstances and have been utiliz...

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