AIMS The aim of this study was to evaluate the influence of environmental conditions on the antifungal activity of the Bacillus sp. CCMI 1053 cultures. METHODS AND RESULTS The electrospray ionization mass spectra (ESI-MS) analysis was used to detect the active peptides produced by Bacillus amyloliquefaciens CCMI 1051 cultures in a glucose-containing medium to which four different nitrogen sou...

The prevalence of invasive fungal infections has increased significantly during organ transplantation, cancer chemotherapy and allogeneic bone marrow transplantation. However, only a limited number of antifungal agents are currently available for the treatment of life-threatening fungal infections. Although new antifungal agents have been introduced in the market, the development of resistance ...

Indigenous actinomycetes isolated from rhizosphere soils were assessed for in vitro antagonism against Colletotrichum gloeosporioides and Sclerotium rolfsii. A potent antagonist against both plant pathogenic fungi, designated SRA14, was selected and identified as Streptomyces hygroscopicus. The strain SRA14 highly produced extracellular chitinase and beta-1,3-glucanase during the exponential an...

abstract a total of 270 bacillus strains were isolated from bulk soil and rhizospheric of cucumber in the tonekabon fields (mazandaran province). antifungal activity of bacillus strains was evaluated against pythium aphanidermatum and p. ultimum using dual culture method. 13 strains with more than 10 mm inhibition zone were selected for further study. morphological, physiological, biochemical a...

Ten metabolites produced by 4 mutants derived from Actinomadura verrucosospora subsp. neohibisca E-40, a high pradimicins producer, were isolated and their structures were determined. Strain JN-219 produced 3 novel analogs of the pradimicin A aglycone, i.e. 11-O-demethyl-7-methoxypradinone II and 11-O-demethylpradinones I and II together with a known aglycone analog, pradinone I, while the meta...

Anthracnose caused by Colletotrichum gloeosporioides is one of most serious fungal diseases on Chinese fir (Cunninghamia lanceolata). Eight endophytes were isolated from a young heathy branch and screened against the pathogen in vitro. One isolate, designated as SMEL1 subsequently identified Epicoccum dendrobii based morphological phylogenetic analyses, suppressed mycelial growth dual-culture p...

Marine ecosystem, covering over 70% of the Earth's area, is the place for a wide variety of animal and plant species whose number greatly exceeds that of terrestrial ones. Amongst those biodiversity, microbial world represents a potential research object to be explored as the recent investigations on marine microbes have given the impact to the entire world as a source of bioactive metabolites ...

[Objective] Screening and identification of a marine-derived actinomycetes with antifugal activity, and then to determine the optimum fermentation conditions. [Method] Candida albicans was used as indicator bacteria to screen active strains. Strain H74-21 was identified based on its morphological, cultural, physiological and sequence analysis of 16S rDNA. HPLC-MS was used to determine the optim...

Fungi and plants are rich sources of thousands of secondary metabolites. The genetically coded possibilities for secondary metabolite production, the stimuli of the production, and the special phytotoxins basically determine the microscopic fungi-host plant interactions and the pathogenic lifestyle of fungi. The review introduces plant secondary metabolites usually with antifungal effect as wel...