Chronic exposure to toxigenic molds in water-damaged buildings is an indoor environmental health problem to which escalating health and property insurance costs are raising a statewide concern in recent times. This paper reviews the structural and functional properties of mycotoxins produced by toxigenic molds and their interactive health implications with antifungal drugs. Fundamental bases of...

Candida is the most common fungal pathogen of humans worldwide and has become a major clinical problem because of the growing number of immunocompromised patients, who are susceptible to infection. Moreover, the number of available antifungals is limited, and antifungal-resistant Candida strains are emerging. New and effective antifungals are therefore urgently needed. Here, we discovered a sma...

A number of benzothiazole-2-ylsulfanyl derivatives 2(1,3-Benzothiazol-2-ylsulfanyl)alkanoylhydrazide (IA – IG) and 5-[1-(1,3-Benzothiazol-2-ylsulfanyl)alkyl]-1,3,4-thiadiazole-2(3H) thione (IIA-IIG) have been synthesised from (1,3Benzothiazol-2-ylsulfanyl)acetic acid. These compounds were synthesied and characterized from their F.T.I.R, and H-NMR spectral studies. The compound (IIA to IIG) were...

Hexane, chloroform and aqueous extracts from Hemidesmus indicus and Ichnocarpus frutescens roots were evaluated for their antimicrobial activity. The chloroform extract of both plants showed antibacterial and antifungal activities against the tested organisms. Both the plants showed highest antibacterial and antifungal activity against Eschericia coli and Aspergillus flavus respectively. With i...