RESUMO O objetivo do presente estudo foi comparar in vitro o efeito da aplicação tópica de flúor na forma de gel acidulado (FFA) ou neutro (FFN) com um dentifrício fluoretado (MFP), na incorporação e ação anticariogênica do flúor. Foram utilizados 125 blocos obtidos de esmalte humano, divididos em 5 grupos de acordo com o tratamento e submetidos à ciclagem de pH durante dez dias. Analisou-se o ...

APF: amicrobial pustulosis of the folds IBD: inflammatory bowel disease IFN-a: interferon-a PPP: palmoplantar pustulosis TNF-a: tumor necrosis factor-a INTRODUCTION Amicrobial pustulosis of the folds (APF) and palmoplantar pustulosis (PPP) are 2 rare autoinflammatory neutrophilic dermatoses. Many studies report PPP triggered by treatment of inflammatory bowel disease (IBD) with tumor necrosis f...

Approximately 1 million people in the United States suffer from interstitial cystitis, a chronic painful urinary bladder disorder characterized by thinning or ulceration of the bladder epithelial lining; its etiology is unknown. We have identified a glycosylated frizzled-related peptide inhibitor of cell proliferation that is secreted specifically by bladder epithelial cells from patients with ...

The energy dependence of intracellular protein breakdown has been recognized for a long time (1,2), but its biochemical mechanisms have begun to be elucidated only recently. This has been initiated by the establishment of several cell-free systems in which protein breakdown is stimulated by ATP (37 ) . We have found previously that the ATP-dependent proteolytic system from reticulocytes is comp...

A unique glycopeptide, antiproliferative factor (APF), has been suggested as a urinary biomarker and potential mediator of long-term bladder disorder Interstitial Cystitis/Painful Bladder Syndrome. There is no known cause for this disease. Several mechanistic approaches have been employed to address the underlying mechanism whereby APF regulates cellular responses in the bladder epithelium. A s...

AIM The purpose of this study was to assess the effect of different surface treatments on the shear bond strength (SBS) of a resin modified glass ionomer cement (RMGIC) to dentin. METHODS AND MATERIALS Forty human third molar teeth were randomly divided into four groups (n=10). The occlusal enamel was removed to obtain a flat surface of dentin. Each group was treated as follows: Group 1: 10% ...

The goal of this prospective longitudinal study was to determine the serological profile of early rheumatoid arthritis (RA), and to test whether antikeratin antibody (AKA), antiperinuclear factor (APF), anti-RA33 antibody and antinuclear antibodies (ANA) had an additional diagnostic value when prescribed after rheumatoid factor (RF)-detecting methods. Sixty-nine patients with early polyarthriti...

It is demonstrated here that cultured fibroblasts release into their medium a nondialyzable, protease-sensitive factor(s) capable of promoting the adhesion and spreading of virus-transformed rat fibroblasts on a plastic substratum. A relatively sensitive biological assay is described for quantitation of the adhesion-promoting factor (APF) activity in serum-free, conditioned medium harvested fro...