This study evaluated apical periodontal healing after root-end sealing using 4-META/MMA-TBB resin (SB), and root-end filling using reinforced zinc oxide eugenol cement (EBA) or mineral trioxide aggregate (MTA) when root canal infection persisted. Apical periodontitis was induced in mandibular premolars of beagles by contaminating the root canals with dental plaque. After 1 month, in the SB grou...

Cdc42 regulates the initial establishment of cytoskeletal and junctional structures, but only little is known about its role at later stages of cellular differentiation. We studied Cdc42's role in vivo in auditory supporting cells, epithelial cells with high structural complexity. Cdc42 inactivation was induced early postnatally using the Cdc42(loxP/loxP);Fgfr3-iCre-ER(T2) mice. Cdc42 depletion...

This communication presents the treatment of 15 cases of c-shaped canals in molars and their treatment outcome with two different obturation methods. The data from 901 patients who received root canal treatment in a molar tooth were examined regarding c-shaped root canals, their treatment and their status one year post op. Among the 901 cases, 15 molars had a c-shaped root canal morphology (1,6...

Apexification with calcium hydroxide is associated with certain difficulties, such as longer treatment time, risk of tooth fracture and incomplete calcification of apical bridge. Mineral trioxide aggregate (MTA) is an alternative material that can be used for apexification of open apices due to its biocompatibility, non-mutagenicity, non-neurotoxicity, regenerative abilities, and good sealing p...

Although radiographic findings at the apical portion of the proximal sesamoid bone (PSB) are often observed in young Thoroughbred foals, conflicting findings, either fractures or apparent secondary ossifications centers, have been reported. Three cases (aged 2, 5, and 7 weeks) were identified in 30 necropsied foals (0-31 weeks old). Histopathologically, the subchondral trabecular woven bone was...

We describe a technical modification of the apical repositioning flap in the conservative surgical treatment of the impacted canine in buccal position. This amendment improves the tooth's eventual visualization, thus permitting a better evolutive follow-up of its eruption process and, most importantly, providing the tooth with buccal attached gingiva that will accompany it in its downward progr...

‘Prognosis’ is the forecast of the course of a disease. In the context of apical periodontitis, therefore, this term applies to both the time course and chances of healing. Over the past 80 years, an extensive volume of studies has been amassed that focuses on the prognosis of apical periodontitis after endodontic therapy. Cumulatively, the authors of these studies have recorded, grouped, and a...

The essential steps for successful endodontic treatment consist of elimination of all diseased pulp and dentin tissues, adequate chemomechanical preparation and filling of the root canal system hermetically.[1] Moreover, it is crucial that root canal obturation has to be limited within root canal system. Minor apical foramen or minor apical constriction is known to be situated 0.5–1.5 mm corona...

INTRODUCTION Thorough cleaning and shaping of root canals are essential for periapical healing. Restoration of endodontically treated teeth is also required for them to function and prevent coronal leakage. This study compared the impact of the quality of root canal treatment versus the quality of coronal restoration in treatment outcomes. METHODS Literature search was conducted using the sea...

The amounts of apical enlargement have been a controversial issue for a long time. The enlargement of the apical part of the canal may severely impact the endodontic prognosis. Enlargement of the apical portion to a larger size may negatively affect the ability to control the filling material during root canal obturation. In addition, an open-apex increases the risk for overfilling which has be...