UNLABELLED A case of a 45 year-old woman who presented with a perianal fistula was reported. Histologically, the excised lesion showed features of apocrine fibroadenoma. In addition, the lesion had both glandular and stromal growth patterns and active chronic inflammation in the background. Malignant or benign counterparts of these types of lesions are widely described in literature. However fi...

The apocrine type of encapsulated papillary carcinoma (ECP-A), of the breast is a rare neoplasm and there are only eight cases reported to date. Herein, we report the ninth case. A 68-year-old Japanese woman presented with a left breast mass. The cytoplasm of the tumour cells showed positive immunostaining for GCDFP-15. Myoepithelial cells were absent within the papillary structures and at the ...

ER: estrogen receptor IMDC: intramammary ductal carcinoma PCAC: primary cutaneous apocrine carcinoma PR: progesterone receptor INTRODUCTION Primary cutaneous apocrine carcinoma (PCAC) is a rare cutaneous adnexal tumor that presents a diagnostic challenge, with histology and staining mirroring those seen in mammary ductal carcinoma and other adnexal neoplasms. We report the first case, to our kn...

A 12-year-old domestic short-haired cat was referred for evaluation of periocular masses. The tail had similar masses and was amputated previously by the referring veterinarian. On examination, multiple pigmented nodules, 3-15 mm in diameter, were found in the periocular skin, primarily involving the palpebral eyelid margin. A wedge excisional biopsy revealed small cuboidal cells forming multip...

Primary cutaneous apocrine carcinoma is a rare adnexal tumor of the skin that occurs mainly in the axilla, anogenital area while the scalp and the lower extremities, especially the thigh, are very unusual sites. However, clinical or pathologic characteristics have not been well established due to a paucity of this tumor. Herein, we report very unusual case of apocrine carcinoma present as a hug...

Two types of glands are found in the outer third of the human earcanal: sebaceous glands that produce sebum and modified apocrine glands that produce apocrine sweat. Together, these substances make up cerumen, which serves to clean, lubricate, and, to some extent, protect the earcanal from bacteria and fungus. Excessive/impacted cerumen can cause tinnitus, vertigo, itching, pain, external otiti...

Primary apocrine adenocarcinoma (AA) is a rare malignant cutaneous neoplasm that typically arises in areas of high apocrine gland density such as the axillae and the anogenital region. Due to the nonspecific clinical manifestation of AA, the differential diagnosis may be broad. The rarity of this neoplasm has led to a relative lack of well-established histologic and immunohistochemical diagnost...

Apocrine breast carcinoma is a rare subtype of the invasive ductal carcinoma and accounts for as little as 0.3-1% of all breast cancers. It is usually positive for human epidermal growth factor receptor 2 (HER-2) and negative for both estrogen receptor and progesterone receptor. Here we present an exceptionally rare case of apocrine breast carcinoma that is a triple receptor negative with metas...