In their publication of the National Institute for Health and Clinical Excellence (NICE) single technology appraisal of eltrombopag, Boyers et al. [1] report the results of the indirect treatment comparison (ITC) of eltrombopag and romiplostim, conducted by GlaxoSmithKline (GSK) [the manufacturer of eltrombopag] and made available to NICE as part of the single technology appraisal of eltrombopa...

This paper presents computational work to detect satire/sarcasm in long commentaries on Italian politics. It uses the lexica extracted from the manual annotation based on Appraisal Theory, of some 30K word texts. The underlying hypothesis is that using this framework it is possible to precisely pinpoint ironic content through the deep semantic analysis of evaluative judgement and appreciation. ...

BACKGROUND Appraisal has evolved to become a key component of workforce management. However, it is not clear from existing proposals for appraisal of doctors whether employers, health authorities or primary care organisations should take responsibility for appraisal processes. AIMS To evaluate the introduction of a pilot peer appraisal system in general practice and to gain insight into the r...

The National Institute for Health and Clinical Excellence (NICE) invited the manufacturer of trastuzumab, Roche Pharmaceuticals, to submit evidence for the clinical and cost effectiveness of this drug for the treatment of advanced gastric cancer (aGC), as part of the Institute's single technology appraisal (STA) process. The Centre for Reviews and Dissemination (CRD) and the Centre for Health E...

This paper examines the performance appraisal system that has been implemented in some public service organisations in line with the changes to a more commercialized structure. In an effort to change the behaviours and attitudes of public servants, performance appraisal systems have incorporated the new values and desired behaviours. Although a myriad of studies exist in regards to the new publ...

Awareness of cognitive dysfunction shown by individuals with Mild Cognitive Impairment (MCI), a condition conferring risk for Alzheimer's disease (AD), is variable. Anosognosia, or unawareness of loss of function, is beginning to be recognized as an important clinical symptom of MCI. However, little is known about the brain substrates underlying this symptom. We hypothesized that MCI participan...

BACKGROUND Medical students in clerkship are continuously confronted with real and relevant patient problems. To support clinical problem solving skills, students perform a Critical Appraisal of a Topic (CAT) task, often resulting in a paper. Because such a paper may contain errors, students could profit from discussion with peers, leading to paper revision. Active peer discussion by a Computer...

Most organizations use performance appraisal system to evaluate the effectiveness and efficiency of their employees. In evaluating staff performance, performance appraisal usually involves awarding numerical values or linguistic labels to employees performance. These values and labels are used to represent each staff achievement by reasoning incorporated in the arithmetical or statistical metho...

BACKGROUND AND PURPOSE In this study, critical appraisal skills of physical therapists who were inexperienced and expert researchers were compared and the effect of the following independent variables on the appraisal skills of novices was examined: years of physical therapy practice, postgraduate experience with research, level of comfort with research, journal reading habits, and content-spec...

BACKGROUND GP appraisal is currently considered inadequate because it lacks robustness. Objective assessment of appraisal evidence is needed to enable judgements on professional performance to be made. AIM To determine GP appraisers' views of the acceptability, feasibility, and educational impact of external peer feedback received on three core appraisal activities undertaken as part of this ...