INTRODUCTION Chronic hepatitis is specified as inflammatory disease of the liver lasting for more than six months. Role of noninvasive fibrosis markers as prognostication factors of the presence or absence of significant fibrosis on liver biopsy of patients with chronic hepatitis is the aim of this study. METHODS Two hundred twenty-one patients with chronic hepatitis involved in the study bet...

OBJECTIVES Various inflammation-based prognostic scores have been associated with poor survival in patients with hepatocellular carcinoma (HCC), and neutrophils display important roles. However, few studies have illuminated the relationship between preoperative aspartate aminotransferase (AST) to neutrophil ratio index (ANRI) and poor prognosis of HCC. We aimed to clarify the prognostic value o...

BACKGROUND We investigated changes in biomarkers of liver disease in HIV-HCV-coinfected individuals during successful combination antiretroviral therapy (cART) compared to changes in biomarker levels during untreated HIV infection and to HIV-monoinfected individuals. METHODS Non-invasive biomarkers of liver disease (hyaluronic acid [HYA], aspartate aminotransferase-to-platelet ratio index [AP...

Hepatic fibrosis; chronic hepatitis C; HCV genotype 4; serum hyaluronic acid (HA); serum Collagen type IV (Coll-IV); AST to platelet ratio index (APRI) and Receiver operating characteristics

Background: Non-invasive markers which use routine laboratory tests are less expensive and highly needed to assess stage liver fibrosis in chronic hepatitis B patients Sub-Saharan Africa. We aimed at evaluating fibrosis, using the Aspartate aminotransferase Platelet Ratio Index (APRI), Fibrosis Based on 4 factors (FIB4), Gamma-glutamyl transpeptidase (GPR) with transient elastography as referen...

OBJECTIVE To determine whether the ratio of first-trimester aspartate aminotransferase (AST) to platelet index (APRI) score will be useful as a new determinant hemolysis, elevated liver enzymes, low platelets (HELLP) syndrome that may develop in later stages pregnancy Study Design: Descriptive-analytical study. PLACE AND DURATION OF STUDY Perinatology Clinic Etlik Zubeyde Hanim Maternity and Wo...

Abstract Background Schistosoma mansoni related hepatic fibrosis is usually associated with hemodynamic alteration increased mortality due to bleeding varices. The diagnosis of varices before imposes a big challenge in resource-limited countries using endoscopy. Published evidence on the utility non-invasive clinical tools predicting presence among patients S. periportal still inadequate includ...

Background: The serum levels of M2BPGi increase with liver fibrosis progression in patients chronic hepatitis B virus (HBV) or C (HCV) infection. However, the diagnostic performance non-alcoholic fatty disease (NAFLD) remains unclear. Objectives: To assess severity NAFLD and healthy controls by using acoustic radiation force impulse (ARFI) as standard reference. Methods: Those suffering from we...

methods fifty-three patients who were treated at the department of gastroenterology and hepatology of the university clinic essen from 2008 to 2013 included in this retrospective study. laboratory parameters were used to calculate non-invasive markers for liver fiibrosis. every patient underwent a liver biopsy within 6 months of the liver stiffness measurement. objectives autoimmune hepatitis (...

Background & aimsLiver biopsy is no viable tool to routinely screen for liver fibrosis in children suffering from chronic intestinal failure (IF). We aim assess the prevalence of a cohort with IF by non-invasive tests: transient elastography (TE), aspartate-aminotransferase-to-platelet-ratio-index (APRI) and enhanced (ELF) score.MethodsCross sectional study where patients IF, receiving parenter...