The study was carried out on goats intoxicated with sodium arsenite @ 2 mg /kg body weight for six months. Results indicate that elevated levels of copper and zinc in tissues were found with respect to increase arsenic concentration. Pathological changes were observed in liver, kidney and brain.

Arsenic poisoning is one of the major causes of chronic human illness and mortality in Bengal Delta plain with limited treatment options.The present study was conducted to evaluate the ameliorating effect of Glycosmis pentaphylla (Rutaceae) leaf extract against sodium arsenite (NaAsO2) induced toxicity. Forty eight adult albino rats were divided into four groups viz.,G0,G1,G2 and G3.Sodium arse...

The objective of this study was to design and evaluate a household-level arsenic education and well water arsenic testing intervention to increase arsenic awareness in Bangladesh. The authors randomly selected 1,000 study respondents located in 20 villages in Singair, Bangladesh. The main outcome was the change in knowledge of arsenic from baseline to follow-up 4 to 6 months after the household...

Explosive increases in skin cancers have been reported in more than 36 million patients with arsenicosis caused by drinking arsenic-polluted well water. This study and previous studies showed high levels of barium as well as arsenic in the well water. However, there have been no reports showing a correlation between barium and cancer. In this study, we examined whether barium (BaCl(2)) may inde...

Arsenic exposure from burning high arsenic-containing coal has been associated with human skin lesion and cancer. However, the mechanisms of arsenic-related carcinogenesis are not fully understood. Inactivation of critical tumor suppression genes by epigenetic regulation or genetic modification might contribute to arsenic-induced carcinogenicity. This study aims to clarify the correlation betwe...

Arsenic exposure produces hepatotoxicity. The common mechanism determining its toxicity is the generation of oxidative stress. Oxidative stress induced by arsenic leads to the activation of nuclear factor erythroid 2-related factor 2 (Nrf2) pathway. (-)-Epigallocatechin-3-gallate (EGCG) possesses a potent antioxidant capacity and exhibits extensive pharmacological activities. This study aims to...