BACKGROUND Familial hyperaldosteronism type I (FH-I) is caused by the unequal recombination between the 11beta-hydroxylase (CYP11B1) and aldosterone synthase (CYP11B2) genes, resulting in the generation of a CYP11B1/B2 chimeric gene and abnormal adrenal aldosterone production. Affected patients usually show severe hypertension and an elevated frequency of stroke at a young age. Aldosterone leve...

Telah dilakukan penelitian pencampuran nano partikel Tempurung Kelapa (TK) yang digunakan sebagai bahan pengisi pada kompon karet dengan tujuan mengetahui sifat mekanik dari berbagai variasi TK. Sifat mekanika meliputi kekerasan, kekuatan tarik dan perpanjangan putus. Metode dalam pembuatan nanopartikel TK adalah metode kopresipitasi. menggunakan mesin open mill komposisi yaitu (0, 2, 4, 6, 8 )...

Many branches of engineering, mathematics, and sciences, have relied on benchmark problems as a standard means to compare different solution techniques. Since 1996, the ASCE Structural Control and Monitoring Committee and Task Group on Benchmark Problems, the U.S. Panel on structural control, and IASCM have developed a series of benchmark control problems that offer a set of carefully modeled r...

A fragility analysis methodology is developed for assessing the response of light-frame wood construction exposed to stipulated extreme windstorms and earthquakes. Performance goals and limit states (structural and nonstructural) are identified from a review of the performance of residential construction during recent hurricanes and earthquakes in the United States. Advanced numerical modeling ...

We previously reported the cellular, functional and cytogenetic characterization of immunoresistant (IR) 13-06-IR29 and 13-06-IR30 human glioma cell clones isolated after immunoselection with alloreactive cytotoxic T lymphocytes (aCTL). Relative to the 13-06-MG parental cells, both clones resisted aCTL lysis at multiple effector to target ratios; the resistant phenotype was maintained for 13-41...

Nine generations of direct selection for ovulation rate (OR) were evaluated to determine the magnitude of the correlated response in three litter size and two litter weight traits. A total of 387 Select line and 394 Control line litters were included in the ten generations of data. Realized heritabili ty of OR was .42 -+ .06 based on the regression of response (SelectControl) on weighted cumula...

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Landslide surges pose a serious threat to the ecological environment and human life safety. Based on rock structure mechanics water sediment dynamics, considering additional resistance caused by interference of loose landslide particles flow structure, this paper deduces calculation formula loose-rock when entering water. It modifies velocity (ASCE) recommended American Society Civil Engineers....

Post operative wound infections have been found to pose a major problem in the field of surgery. Advances in control of infection have not completely eradicated this problem because of development of drug reistance. The present study was carried out in Index Medical College hospital, one year study. 100 patients were recruited who underwent surgery in the orthopedic, obstetrics and gynecology a...