amyloid-β (aβ) self-assembly into cross-β amyloidfibrils is implicated in a causative role in alzheimer’s disease pathology.uncertainties persist regarding the mechanisms of amyloid self assembly and the role of metastable prefibrillar aggregates. aβ fibrilsfeature a sheet-turn-sheet motif in the constituent β-strands; as such, turn nucleation has been proposed as a rate-limiting step in the se...

This paper presents an extended classification for non-permutation flowshops. The versatile options which occur with the possibility of resequencing jobs within the line are considered. The literature review shows that no classification exists which considers extensively this type of flowshop.

In this paper, we address the problem of two-machine flowshop scheduling problem with sequence independent setup times to minimize the total completion time. We propose five new polynomial lower bounds. Computational results based on randomly generated data show that our proposed lower bounds consistently outperform those of the literature.

This paper represents linkage network of queues consisting of biserial and parallel servers linked to a common server in series with a flowshop scheduling system consisting of two machines. The significant transportation time of the jobs from one machine to another is also considered. Further, the completion time of jobs/customers (waiting time + service time) in the queue network is the set...

This paper deals with the permutation flowshop scheduling problem time lags constraints to minimize total weighted tardiness criterion by using Branch and Bound algorithm. A new lower bound was developed for problem. The computational experiments indicate that proposed algorithm provides good solution in terms of quality requirements.