neuroplasticity is the brain's ability to reorganize itself by forming new neural connections throughout life. neuroplasticity allows the neurons in the brain to compensate injury and disease and to adjust their activities in response to new situations or to changes in their environment. at the other side, it is now well established that neuronal function is strongly influenced by both cen...

BACKGROUND Individuals with autism put a heavy demand on medical services, and prevalence estimates are needed for the planning of such services. Screening for autism in children has important implications for individuals and policy makers. This study aimed to estimate prevalence of suspected autism in children in Longhua District, Shenzhen, and to investigate risk factors for autism. METHODS...

BACKGROUND Autism spectrum conditions (autism) are diagnosed more frequently in boys than in girls. Females with autism may have been under-identified due to not only a male-biased understanding of autism but also females' camouflaging. The study describes a new technique that allows automated coding of non-verbal mode of communication (gestures) and offers the possibility of objective, evaluat...

trying to reduce clinical problems in children autism through education of parents in recent years has been addressed by researchers. this study aimed to investigate the effectiveness of training of pivotal response treatment (prt) to mothers with 6 to 12 year old autistic children on reducing the autism symptoms. also, the impact of prt on reduction of parenting stress was addressed in this st...

aim and background: deficit of theory of mind is a fundamental impairment of social skill in autistic children. the purpose of present study was evaluation of cognitive rehabilitation on social cognition abilities of children with high function autism. methods and materials: in present single subject study, 4 children with high function autism participated in study with no probably sampling. si...

background: transforming growth factor-β1 (tgf-β1) has been found to play a crucial role in early central nervous system development. several studies have illustrated decreased tgf-β1 levels in sera and brains of autistic children. two point mutations in the tgf-β1 signal peptide at 869t/c and 915g/c have been reported to influence tgf-β1 expression. the aim of the present study was to investig...

Genetic syndrome groups at high risk of autism comorbidity, like Down syndrome and fragile X syndrome, have been presented as useful models for understanding risk and protective factors involved in the emergence of autistic traits. Yet despite reaching clinical thresholds, these ‘syndromic’ forms of autism appear to differ in significant ways from the idiopathic or ‘non-syndromic’ autism profil...

Background: Many studies reported high incidence of epileptiform discharges in children with autism, but with different rates and different patterns, few studies done for children with idiopathic autism. Aime of work: is to study the pattern of subclinical epileptiform discharge, and its clinical correlations for childern with idiopathic autism. Patients and methods: 47 children with idiopathic...

Autism prevalence has risen dramatically over the past two decades in California. Although often suggested to have been crucial to the rise of autism, environmental and social contextual drivers of diagnosis have not been extensively examined. Identifying the spatial patterning of autism cases at birth and at diagnosis can help clarify which contextual drivers are affecting autism's rising prev...

BACKGROUND The inheritance pattern in most cases of autism is complex. The risk of autism is increased in siblings of children with autism and previous studies have indicated that the level of risk can be further identified by the accumulation of multiple susceptibility single nucleotide polymorphisms (SNPs) allowing for the identification of a higher-risk subgroup among siblings. As a result o...