نتایج جستجو برای: autoimmune encephalitis

تعداد نتایج: 82815  

Journal: :Journal of Postgraduate Medical Institute 2023

The most common type of autoimmune encephalitis is anti-NMDAR-encephalitis. It characterized by IgG an­tibodies against the GluN1 subunit NMDA receptor, leading to marked neuropsychiatric and behavioural symptoms that progress in a subacute manner seizures, speech abnormalities, depressed level con­sciousness. In this case report, clinical course 30-year-old man who first received treatment for...

2017
Ko Tsutsui Takashi Kanbayashi Manabu Takaki Yuki Omori Yumiko Imai Seiji Nishino Keiko Tanaka Tetsuo Shimizu

The symptoms of catatonia have been reported to be similar to the initial symptoms of anti-N-methyl-D-aspartate receptor (NMDAR) encephalitis. Subsequently, this autoimmune limbic encephalitis has been noticed by many psychiatrists. For a differential diagnosis of catatonic state, it is important to detect anti-NMDAR encephalitis. This encephalitis is expected to be in remission by early detect...

Journal: :Neurology 2003
Y Takahashi H Mori M Mishina M Watanabe T Fujiwara J Shimomura H Aiba T Miyajima Y Saito A Nezu H Nishida K Imai N Sakaguchi N Kondo

BACKGROUND Antibody-mediated and cytotoxic T cell-mediated pathogenicity have been implicated as the autoimmune pathophysiologic mechanisms in Rasmussen's encephalitis. METHODS The authors investigated autoantibodies against the NMDA glutamate receptor (GluR) epsilon2 subunit and their epitopes in serum and CSF samples from 15 patients with chronic epilepsia partialis continua (EPC), 17 with ...

2014
Florian Wegner Florian Wilke Peter Raab Said Ben Tayeb Anna-Lena Boeck Cathleen Haense Corinna Trebst Elke Voss Christoph Schrader Frank Logemann Jörg Ahrens Andreas Leffler Rea Rodriguez-Raecke Reinhard Dengler Lilli Geworski Frank M Bengel Georg Berding Martin Stangel Elham Nabavi

BACKGROUND Pathogenic autoantibodies targeting the recently identified leucine rich glioma inactivated 1 protein and the subunit 1 of the N-methyl-D-aspartate receptor induce autoimmune encephalitis. A comparison of brain metabolic patterns in 18F-fluoro-2-deoxy-d-glucose positron emission tomography of anti-leucine rich glioma inactivated 1 protein and anti-N-methyl-D-aspartate receptor enceph...

2014
Florian Wegner Florian Wilke Peter Raab Said Ben Tayeb Anna-Lena Boeck Cathleen Haense Elke Voss Christoph Schrader Frank Logemann Jörg Ahrens Andreas Leffler Rea Rodriguez-Raecke Reinhard Dengler Lilli Geworski Frank M Bengel Georg Berding Martin Stangel Elham Nabavi

Background: Pathogenic autoantibodies targeting the recently identified leucine rich glioma inactivated 1 protein and the subunit 1 of the N-methyl-D-aspartate receptor induce autoimmune encephalitis. A comparison of brain metabolic patterns in F-fluoro-2-deoxy-d-glucose positron emission tomography of anti-leucine rich glioma inactivated 1 protein and anti-N-methyl-D-aspartate receptor encepha...

Journal: :Cureus 2021

Checkpoint inhibitors (CPI) have become mainstream in standard therapy various tumors, especially malignant melanoma. Despite their widespread beneficial effects, these are also notorious for immune-related adverse events (irAEs). Hemophagocytic lymphohistiocytosis (HLH) is an aggressive and life-threatening syndrome of excessive immune activation. We report a case 33-year-old male having histo...

Journal: : 2023

Background: During the new COVID-19 coronavirus infection pandemic, a growing incidence of autoimmune encephalitis cases has been observed. One primary problems related to patients with this highly lethal pathology is its timely early diagnostics and prescription an optimal individual course immunotherapy. In debut anti-NMDA receptor (inotropic glutamate receptor, selectively binding N-methyl D...

Journal: :Frontiers in bioscience 2018
Hsiuying Wang

Anti-N-methyl-D-aspartate (Anti-NMDA) receptor encephalitis is an acute autoimmune neurological disorder that can be triggered by virus, H1N1/tetanus/diphtheria/pertussis and polio vaccines or by presence of a tumor. The association between anti-NMDA receptor encephalitis and Japanese encephalitis vaccination was examined and a general protocol of phylogenetic method which details the steps and...

2013
Juliana Lockman Kenneth Laxer

Rasmussen's encephalitis (RE), or chronic focal encephalitis, is a progressive neurologic condition consisting of cognitive regression, hemiparesis, and intractable epilepsy. While the etiology is unknown, evidence supports an autoimmune basis. Although steroids, plasmapheresis, and intravenous immunoglobulin (IVIg) may afford limited benefit, standard of care for pediatric cases typically invo...

Journal: :Turk psikiyatri dergisi = Turkish journal of psychiatry 2013
Nedia Ben Achour Ilhem Ben Youssef-Turki Meriem Messelmani Ichraf Kraoua Jihene Yaacoubi Hedia Klaa Aida Rouissi Hanen Benrhouma Malika Ben Ahmed Adrien Didelot François Ducray Neziha Gouider-Khouja

Anti-NMDA receptor (NMDAR) encephalitis has only recently been described as a cause of paraneoplastic and autoimmune encephalitis (Dalmau et al. 2008). Herein we present a 13-year-old girl with NMDAR encephalitis characterized by acute mania at onset, which was initially misdiagnosed as a primary psychiatric disorder. No evidence of a tumor was found. Intravenous immunoglobulin (IVIG) was admin...

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