chronic urticaria is the most common skin diseases, characterized by chronic cutaneous lesions which severely debilitates patients in several aspects of their everyday life. vitamin d is known to exert several actions in the immune system and to influence function and differentiation of mast cells, central role players in the pathogenesis of chronic idiopathic urticaria. this study was performe...

Chronic urticaria (CU) in children often is caused by physical triggers. It also can be associated with autoimmune disease, especially thyroid autoimmunity. Functional autoantibodies against FcepsilonRIalpha have been reported in children with CU but have not been studied in a systematic fashion. The autologous serum skin test has been proposed as a surrogate test to define the presence of thes...

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Chronic idiopathic urticaria (CIU) is characterized by multiple swollen raised areas on the skin that are intensely itchy. These lesions can last less than 24 hours and persist for more than 6 weeks. CIU affects 0.5-1 % of the population and causes a signifi cant decrease in the quality of life. The major advance in our understanding of CIU in recent years has been the discovery that in 30-50 %...

Results Case A 30-year-old Thai woman, who presented with a history of angioedema for 6 months. Her angioedema involved lip, eyelid and hand swelling. She was referred to our Allergy Clinic for further investigation. It was found that her symptoms of angioedema usually occurred in 30 minutes after ingesting navel orange and disappeared after 1-2 hours later. She favored in navel orange and she ...

Background In patients allergic to penicillin only a minority of those who have specific IgE against penicillin also have a positive intracutaneous test (ICT) to penicillin and vice versa. This is in contrast to findings in patients with allergy to classical type 1 allergens, e.g. grass or peanuts. Besides that, our investigations indicates that histamine is only released in the minority of pos...

background: diagnosis of food allergy is difficult in children. food allergies are diagnosed using several methods that include medical histories, clinical examinations, skin prick and serum-specific immunoglobulin e (ige) tests, radio-allergosorbent test (rast), food challenge, and supervised elimination diets. in this study we evaluated allergies to cow's milk, egg, peanut, and fish in c...