The concept of 'equipoise', or the 'uncertainty principle', has been represented as a central ethical principle, and holds that a subject may be enrolled in a randomized controlled trial (RCT) only if there is true uncertainty about which of the trial arms is most likely to benefit the patient. We sought to estimate the frequency with which equipoise conditions were met in industry-sponsored RC...

In ‘The Choice Theory of Contracts’, we advance a claim about the centrality autonomy to contract. Since publishing Theory, have engaged dozens reviews and responses; here, reply Robert Stevens, Arthur Ripstein, Brian Bix. All this rigorous debate confirms for us one core point: contract’s ultimate value must be autonomy, properly understood refined. Autonomy is telos contract its grounding pri...

IMPACTThis article analyses the democratic autonomy of local public actors in collaborative organizational arrangements within context European Social Investment Fund (ESIF). The authors outline three different ways that collaborations materialize and analyse how these influence a municipality’s capacity to set policy priorities decide upon matters. study shows varies partnerships depending on ...

This paper examines Yilmaz, Ören and Aghaee's outline of present research efforts into the development of simulations that " represent the behavior of active (human) entities in the world. " The paper argues that the Carter-Bostrom formulation of the anthropic principle provides a more functional set of theoretical, and pragmatic proposals to frame the issue of the simulation of human sociocogn...

Our aim in the present paper is to approach the nature of life from the perspective of autonomy, showing that this perspective can be helpful for overcoming the traditional Cartesian gap between the physical and cognitive domains. We first argue that, although the phenomenon of life manifests itself as highly complex and multidimensional, requiring various levels of description, individual orga...

Imposing artificial feeding on people with anorexia nervosa may be unethical. This seems to be Heather Draper's suggestion in her article, 'Anorexia Nervosa and Respecting a Refusal of Life-Prolonging Therapy: A Limited Justification.' Although this is an important point, I shall show that the arguments supporting this point are flawed. Draper should have made a brave claim: she should have cla...

The management of mineral and coal resources is affected by the shift in paradigm regional government administration, which now emphasizes aspects autonomy. Law Number 23, 2014 concerning Regional Government, genuinely adheres to maxim maximal autonomy, appears be incompatible with 3, 2020 revision 4, 2009 on Mineral Coal Mining. In practice, this results a variety interpretations nature signif...

Christian List (London School of Economics) and Peter Menzies (Macquarie University) (forthcoming in the Journal of Philosophy) ABSTRACT It is often argued that higher-level special-science properties cannot be causally efficacious since the lower-level physical properties on which they supervene are doing all the causal work. This claim is usually derived from an exclusion principle stating th...