Abstract Background FREEDOM-C and FREEDOM-C2 were randomized, placebo-controlled, double-blinded international, multicenter studies investigating the use of oral treprostinil (TRE) in subjects on mono or dual background pulmonary arterial hypertension (PAH) therapies. Both had a primary endpoint change 6-minute walk distance (6MWD) at Week 16 vs baseline. Previous post-hoc analyses combining th...

Introduction: Head scans are the most frequently performed computed tomography (CT) examinations worldwide. However, there is growing concern over the probability of increased cancer risks among the exposed populations. Diagnostic reference levels (DRLs) identify radiation dose that is not commensurate with clinical objectives. The aim of this study was to establish DR...

background:  radiochromic film is used for radiation dose measurement, xr-rv3 is used in fluoroscopy and ebt2 film in radiation therapy. the aim was to determine if the dosimetric properties of these two films are comparable in megavolt photon beams. materials and methods: comparison measurements included: calibration curves, heterogeneous phantom dose profiles, and nasopharynx dose distributio...

PURPOSE The gradient-optimized methods are overcoming the traditional feathering methods to plan field junctions in craniospinal irradiation. In this note, a new gradient-optimized technique, based on the use of a background dose, is described. METHODS Treatment planning was performed by RayStation (RaySearch Laboratories, Stockholm, Sweden) on the CT scans of a pediatric patient. Both proton...

Determining ionizing radiation in a geographic area serves to assess its effects on a population's health. The aim of this study was to evaluate the spatial distribution of the background environmental outdoor gamma dose rates in Chihuahua City. This study also estimated the annual effective dose and the lifetime cancer risks of the population of this city. To determine the outdoor gamma dose r...