Background: Nowadays, it is needed to explore new routes to treat infectious bacterial pathogens due to prevalence of antibiotic-resistant bacteria. Antimicrobial photothermal therapy (PTT), as a new strategy, eradicates pathogenic bacteria.Objective: In this study, the antimicrobial effects of a carbon nanoparticles-polypyrrole nanocomposite (C-PPy) upon laser irradiation were investigat...

Reactive oxygen intermediates generated by neutrophils kill bacteria and are implicated in inflammatory tissue injury, but precise molecular targets are undefined. We demonstrate that neutrophils use myeloperoxidase (MPO) to convert methionine residues of ingested Escherichia coli to methionine sulfoxide in high yield. Neutrophils deficient in individual components of the MPO system (MPO, H(2)O...

background: xanthomonas citri subsp. citri (xcc), the causative agent of bacterial citrus canker, has affected citriculture worldwide. varieties of means have been used to minimize its devastating effects, but no attention has been given to bacteriocins.objectives: here and for the first time, we report the isolation and characterization of two novel bacteriocins.materials and methods: secretom...

The bacterial PTE is able to catalyze the hydrolysis of a wide range of organophosphate nerve agents. The active site has been shown to consist of a unique binuclear metal center that has evolved to deliver hydroxide to the site of bond cleavage. The reaction rate for the hydrolysis of activated substrates such as paraoxon is limited by product release or an associated protein conformational ch...

the possibility of manufacturing and effects of a slow release non-protein nitrogen product on ruminant nutrition were evaluated in two separate experiments. in first experiment, making of slow release component was followed by connecting branched carbon chain to the molecule of urea to reduce the degree of solubility. then, the sample product was analyzed to assess its chemical structure, and ...

Abstract Background Protein secretion in bacteria is an attractive strategy for heterologous protein production because it retains the high titers and tractability of bacterial hosts while simplifying downstream processing. Traditional intracellular strategies require cell lysis separation product from chemically similar cellular contents, often a multi-step process that can include expensive r...

An untapped therapeutic target for chronic wounds is the skin microbiota. Thus far, wound treatments have focused on eliminating pathogenic microbes, such as Staphylococcus aureus, that are known to delay healing. However, it not well understood how non-pathogenic bacterial colonization modulates healing, and if any colonizing bacteria confer a beneficial response. To initiate an investigation,...

conclusions these results show the usefulness of proteome analysis in successful identification of the common proteins between n. lactamica strains and nmb. this proteomics analysis is the starting point in the path of knowledge development about whole proteome profiles of n. lactamica strains. objectives the main aims of this study were to determine whole proteome profiles of n. lactamica stra...