Twenty-four mutacin-producing Streptococcus mutans strains were screened for their propensity to produce class II one-peptide bacteriocin using a deferred antagonism assay. Streptococcus salivarius and 3 mutants defective in their mannose phosphotransferase systems (mannose-PTS) were used as sensitive strains to identify which mannose-PTS could act as the docking site for class II one-peptide b...

Lactic acid bacteria serve as important human probiotics, they can produce bacteriocins from different dairy sources, and the antimicrobial activity of their have been documented in scientific field. This study aimed to assess activities bacteriocin obtained sources. An experimental analytical design was used isolate species on de Man, Rogosa Sharpe Media, identify them phenotypically evaluated...

Background: Bacteriocin is a peptidic toxin has many advantages to bacteria in their ecological niche and strong antibacterial activity. Objective: The aim of this study was evaluation bacteriocin using Streptococcus sanguinis isolated from human dental caries. Subjects Methods: Thirty five streptococcus isolates were diagnosed tested for production bacteriocin, then the optimal conditions dete...

A recent comparative genomic hybridization study in our laboratory revealed considerable plasticity within the bacteriocin locus of gastrointestinal strains of Lactobacillus salivarius. Most notably, these analyses led to the identification of two novel unmodified bacteriocins, salivaricin L and salivaricin T, produced by the neonatal isolate L. salivarius DPC6488 with immunity, regulatory and ...

Bacteriocin producing Lactobacillus acidophilus and Pediococcus acidilactici were isolated from milk and meat samples, respectively. An attempt was made to produce bacteriocin in a Dairy Based (DB) medium using these organisms. Higher bacteriocin activity was shown by L. acidophilus in the DB medium. Bacteriocins of both the organisms were effective against food pathogens. The bacteriocins were...

Article history: Received on: 10/04/2014 Revised on: 06/05/2014 Accepted on: 19/05/2014 Available online: 27/05/2014 In this study, Pediococcus pentosaceus VTCC-B-601 was investigated and characterized for bacteriocin production. The antimicrobial activities were produced strongly at the late exponential phase (5x10 CFU/ml), corresponding to the activity of cephalosporin (13.3μg/ml) against Sal...

Carnobacteriocin B2 is a well-characterized class II bacteriocin produced by a 61-kb plasmid from Carnobacterium piscicola LV17. Export of this bacteriocin is dependent on specific ABC (ATP-binding cassette) secretion proteins. Divergicin A is a strongly hydrophobic narrow-spectrum bacteriocin produced by a 3.4-kb plasmid from Carnobacterium divergens LV13. Predivergicin A contains a signal pep...

background :    proteus spp. belongs to the family of enterobacteriaceae . these bacteria are gram-negative and motile microorganisms and known as the third most common causes of urinary tract infections. the aim of the current study was to investigate the effects of some secondary metabolites from probiotic strains of lactobacillus spp. on swarming and growth of proteus mirabilis and p. vulgar...

Bacteriocins produced by lactic acid bacteria (LAB) are expected to be safe antimicrobial agents. While the best studied LAB bacteriocin, nisin A, is widely utilized as a food preservative, various novel ones are required to control undesirable bacteria more effectively. To discover novel bacteriocins at the early step of the screening process, we developed a rapid screening system that evaluat...

A fusion between the pCloDF13-derived bacteriocin release protein and beta-lactamase was constructed to investigate the subcellular localization and posttranslational modification of the bacteriocin release protein in Escherichia coli. The signal sequence and 25 of the 28 amino acid residues of the mature bacteriocin release protein were fused to the mature portion of beta-lactamase. The hybrid...