Magnetic resonance imaging (MRI) can be used to detect lesions in the brains of multiple sclerosis (MS) patients and is essential for diagnosing the disease and monitoring its progression. In practice, lesion load is often quantified by either manual or semi-automated segmentation of MRI, which is time-consuming, costly, and associated with large inter- and intra-observer variability. We propos...

Distinguished Contributors The "OASIS Distinguished Contributor" designation is awarded to a select group of OASIS members who have made significant contributions to the advancement of open standards. We gratefully acknowledge these outstanding individuals for their impact on the global information society.

OBJECTIVE To review the evidence relating to obstetrical anal sphincter injuries (OASIS) with respect to diagnosis, repair techniques and outcomes. To formulate recommendations as to patient counselling regarding route of delivery for subsequent pregnancy after OASIS. OPTIONS Obstetrical care providers caring for women with OASIS have the option of repairing the anal sphincter using end-to-en...

BACKGROUND Vascular endothelial growth factor-A (VEGFA) is the main mediator of angiogenesis. Angiogenesis plays important roles not only in many physiological processes, but also in the pathophysiology of many diseases. VEGFA is one of the therapeutic targets of treatment for ocular diseases with neovascularization. Therefore, elucidation of the regulatory mechanisms for VEGFA expression is im...

Palynomorphs extracted from the mud coffins and plant remains preserved at the archaeological site of Xiaohe Cemetery (Cal. 3980 to 3540 years BP) in Lop Nur Desert of Xinjiang, China were investigated for the reconstruction of the ancient environments at the site. The results demonstrate that the Xiaohe People lived at a well-developed oasis, which was surrounded by extensive desert. The veget...

Agriculture of the inland arid region in Xinjiang depends on irrigation, which forms oasis of Northwest China. The production and water use of wheat, a dominant crop there, is significantly affected by undergoing climate variability and change. The objective of this study is to quantify inter-annual variability of wheat yield and water use from 1955 to 2006. The farming systems model APSIM (Agr...

We assessed the total nitrogen (N) concentrations of 28 still surface water (lake and pond), and 42 flowing surface water (river), monitoring sites under 29 typical terrestrial ecosystems of the Chinese Ecosystem Research Network (CERN) using monitoring data collected between 2004 and 2009. The results showed that the median total N concentrations of still surface water were significantly highe...

BACKGROUND The association between birth position and obstetric anal sphincter injury (OASIS) in spontaneous vaginal deliveries is unclear. METHODS The study was based on the Stockholm-Gotland Obstetric Database (Sweden) from Jan 1(st) 2008 to Oct 22(nd) 2014 and included 113 279 singleton spontaneous vaginal births with no episiotomy. We studied risk of OASIS with respect to the following bi...

Dorothy Euwards, PhD, is Coordinator of Research, De· partment of Occupational Therapy, and Carolyn Manville Baum, MA, OTR, FAOTA, is Director of Occupational Therapy Clinical Services, both at the Irene Walter John· son Institute of Rehabilitation, Washington University Medical School, SI Louis, Missouri. Dorothy Edwards and Carolyn Manville Baum also are members of the OASIS AdVisory Committe...

UNLABELLED Oasis is a web application that allows for the fast and flexible online analysis of small-RNA-seq (sRNA-seq) data. It was designed for the end user in the lab, providing an easy-to-use web frontend including video tutorials, demo data and best practice step-by-step guidelines on how to analyze sRNA-seq data. Oasis' exclusive selling points are a differential expression module that al...