Neoplastic lesions of the skin are among the most common human malignancies. They originate from different skin tissues and structures such as:  epidermis  skin appendages (hair follicles, sebaceous glands, eccrine sweat glands, apocrine sweat glands)  pigment cells (melanocytes)  mesenchymal structures (fibrous tissue, fatty tissue, blood and lymphatic vessels, muscles)  nerves and APUD c...

nodules that reside within the dermis and frequently demonstrate epidermal attachment. Multifocal lobules of varying size and shape exhibit peripheral palisading and central haphazard array of cells.The entire tumor demonstrates an expansile growth pattern. Cystic degeneration or central necrosis may be prominent. Although similar to the nodular variant, micronodular basal cell carcinoma is com...

8. Makker R, Ramesh V. On the diagnosis of facial granulomatous dermatoses of obscure origin. International Journal of Dermatology. 2005;44:606-9. 9. Helm KF, Menz J, Gibson LE, Dicken CH. A clinical and histopathologic study of granulomatous rosacea. J Am Acad Dermatol. 1991;25:1038-43. 10. Cribier B, Lieber-Mbomeyo A, Lipsker D. Clinical and histological study of a case of facial Afro-Caribbe...

Basal cell carcinoma is the most common skin cancer in the Caucasian population. The cancer arises in sun exposed areas of the skin. The incidence of morbidity is high and it is still growing. The metastatic rate is low, but the enlarging tumor may cause severe tissue disfigurement and a poor cosmetic outcome. The diagnosis is usually clinical but there are many subtypes of this carcinoma and c...

Basal cell carcinoma (BCC) is the most common type of skin cancer (75% to 80%) and the most common of all cancers (more than one out of every three new cancers). Seventy to eighty percent of BBC occurs in the head and neck region, followed by the trunk (about 25%), and penis, vulva, or perianal skin (about 5%). It is more common in light-skinned individuals (type 1 or type 2 skin) with a family...

A. Environmental factors 1. Non-Ionizing Radiation – Ultraviolet (UVA & UVB) Two wavelength “types” of UV reach the earth’s surface – UVA (320-400nm) and UVB (290-320nm). Most of the UVB and all UVC are filtered by stratospheric ozone. UVA was initially thought to be noncarcinogenic, but is now thought to be a potent co-carcinogen with UVB. Recently, high dose UVA (as found in tanning beds) has...

Basal cell carcinoma (BCC) is the most common non-melanoma skin cancer. Exposure to ultraviolet light is an important risk factor for BCC development and the disorder therefore develops commonly on body areas that are more exposed to sunlight, such as the face and neck. It is uncommon in the closed area of the body and quite rare in the perianal and genital regions. Herein, we report a 34-year-...

histopathologic study of granulomatous rosacea. J Am Acad Dermatol. 1991;25:1038–43. 10. Cribier B, Lieber-Mbomeyo A, Lipsker D. Clinical and histological study of a case of facial Afro-Caribbean childhood eruption (FACE). Ann Dermatol Venereol. 2008;125: 663–7. 11. Misago N, Nakafusa J, Narisawa Y. Childhood granulomatous periorificial dermatitis: lupus miliaris disseminatus faciei in children...