Serogroup B is the only major disease-associated capsular group of Neisseria meningitidis for which no protein-polysaccharide conjugate vaccine is available. This has led to the development of multi-component protein-based vaccines that target serogroup B invasive meningococcal disease (IMD), including Bexsero®, which was implemented for UK infants in 2015, and Trumenba®. Given the diversity of...

Effective utilization of agricultural and industrial wastes has attracted increasing attention due to the promotion sustainability circular economy in our society. In this study, we investigated an economical environmentally friendly decortication method using metal oxide-assisted hydrogen peroxide oxidization separate hemp bast hurd from wasted (Cannabis sativa) stalk. With various chemical pr...

Die sich beschleunigende technologische Entwicklung der letzten Jahrzehnte und die zunehmende digitale Vernetzung erhöhen den Bedarf an qualitativ hochwertigen, aktuellen und zuverlässigen Verkehrsdaten. Mit der MDM-Initiative hat die Bundesanstalt für Straßenwesen (BASt) auf diese Entwicklung reagiert und mit dem MobilitätsDatenMarktplatz (MDM) eine universelle Plattform zum Austausch von Verk...

3901 Reduction of Streptozotocin Toxicity by 3-0Methyl-i-glucose with Enhancement of Antitumor Activity in Murine L1210 Leukemia. Michael M. Wick, Aldo Rossini, and David Glynn. *3904 Interindividual and lntraindividual Variations in Aryl Hydrocarbon Hydroxylase in Monocytes from Monozygotic and Dizygotic Twins. T. Okuda, Elliot S. Vesell, E. Plotkin, A. Tarone, Robert C. Bast, and Harry V. Gel...

Reliable distributed systems involve many complex protocols. In this context, protocol composition is a central concept, because it allows the reuse of robust protocol implementations. In this paper, we describe how the Strategy pattern has been recursively used to support protocol composition in the BAST framework. We also discuss design alternatives that have been applied in other existing fr...

We reconsider the concept of transit nodes as introduced by Bast et al. [3] and for the first time construct instance based lower bounds on the size of transit node sets by interpreting a LP formulation of the problem and its dual. As a side product we achieve considerably smaller access node sets which directly influences the query time for non-local queries.