Scholars and public health officials alike have expressed significant concern over the dramatic growth in suicide among young Black males. Work in this area has focused primarily on the 1980s and early 1990s as key evidence of this concern. In the current study, we use a longer time series from 1982 to 2001 to examine exactly what these suicide trends look like as well as how and why they vary ...

Background—Alterations in Ca-handling proteins are thought to underlie the deranged Ca transients that contribute to deterioration of cardiac function in congestive heart failure (CHF). Clinical trials in CHF patients have shown that treatment with b-adrenergic receptor antagonists (bB) improves cardiac performance. The present study determined whether the abundance of Ca-handling proteins is d...

b a ckground:  the purpose of our study was to investigate the possible effect of  bsm i vitamin d receptor (vdr’s) polymorphism on changes of the inflammatory and oxidative stress (os) biomarkers in response to daily intake of vitamin d- fortified yogurt drink ( doogh ) in subjects with type 2 diabetes (t2d). m ethods : in a randomized controlled trial, 100 t2d subjects were allocated to two g...

When beta adrenergic receptor blocker (BB) is stopped abruptly, tachycardia, blood pressure raise, increased number of anginal attacks, worsening of HF symptoms, etc. may ensue, which is known as “BB rebound phenomenon”. Thus, the aim of the paper is four-fold: to review the topic (BB rebound phenomenon); to illustrate BB rebound presence in everyday practice; to provide Guidelines’ view on BB ...

This year, 2004, will see political realignments that will affect gun-owner rights for years to come. The current Bush administration has been a period of inertia in terms of advancing new controls, but this is largely due to the administration being distracted by the War on Terror. During his campaign for the presidency in 2000, Bush favored extending the “assault-weapons” ban of 1994 that sun...

Background Gun shows are an important source of firearms, but no adequately powered studies have examined whether they are associated with increases in firearm injuries. Objective To determine whether gun shows are associated with short-term increases in local firearm injuries and whether this association differs by the state in which the gun show is held. Design Quasi-experimental. Setti...

We have isolated a variant of human immunodeficiency virus type 1 (HIV-1) which is highly infectious to fibroblastlike cells (BT cells) derived from human brain as well as CD4-positive T cells. This variant HIV-1, named HIV[GUN-1V], was obtained by infecting BT cells with a prototype HIV-1 isolate, named HIV[GUN-1WT], which is highly infectious to T cells but barely infectious to BT cells. HIV[...

The finding that liver necrosis caused by the environmental glutathione (GSH)-depleting chemical, bromobenzene (BB) is associated with marked impairment in O- and S-methylation of BB metabolites in Syrian hamsters raises questions concerning the role of methyl deficiency in BB toxicity. N-Acetylmethionine (NAM) has proven to be an effective antidote against BB toxicity when given after liver GS...