objective primary central nervous system lymphoma (pcnsl) is an extremely rare condition in childhood. we report the first case of pcnsl in a child in iran. clinical presentation a nine-year-old boy was referred to mofid hospital with the history of headache of four months and seizure of 2 months duration. magnetic resonance imaging of the brain revealed a hyper-intense lesion in left fronto-pa...

BACKGROUND According to the current World Health Organization Classification of Lymphoid Tumours, follicular lymphoma is subclassified into three grades according to the number of centroblasts. Follicular lymphoma grade 3 can be further divided into types A and B. Almost all available genetic data on grade 3B follicular lymphomas have been generated from tumors with an additional diffuse large ...

INTRODUCTION More and more drugs for cancer are being developed targeting signaling transduction pathways, and some of these agents are already in clinical trials. A noninvasive method for early detection of the effect of these drugs is required. NMR is a promising candidate to meet this need as it can be applied in vivo to detect metabolic perturbations in tumors following therapy. We have bee...

Ocular involvement in lymphoma is a relatively rare condition that can result from a primary intraocular lymphoma or an intraocular manifestation of systemic lymphoma. Lymphoma manifestations frequently masquerade as other more benign intraocular conditions including allergic or infectious conjunctivitis, uveitis, multiple evanescent white dot syndrome, acute retinal necrosis, or herpetic retin...

Proteins of the B-cell lymphoma 2 family are crucial for the regulation of apoptosis. B-cell lymphoma 2-associated X is a pro-apoptotic protein, while B-cell lymphoma 2 protein opposes apoptosis. The influence of 1 microM 2-methoxyestradiol was investigated on the expression levels of these two proteins in MCF-7 cells. 2-Methoxyestradiol exposure did not influence B-cell lymphoma 2 protein expr...

  Primary Hepatic Lymphoma (PHL) is rare and possibly associated with viral hepatitis and autoimmune diseases. Scleroderma could exceptionally be complicated by lymphoma. We describe PHL occurring in a 52-year-old female suffering scleroderma for eight years, with no history of cytotoxic or high-dose glucocorticoid therapy. CT scan, performed to work-up abdominal discomfort, constipation, and ...

Abstract Background Acral vascular syndrome clinically presents as digital ischemia with Raynaud’s phenomenon and erythromelalgia but can be rarely seen in the malignant condition. Patients may present pain, permanent blanching or cyanosis, desquamation ulceration of fingers. is associated lymphoid neoplasm smoking, autoimmune connective tissue diseases, vasculitis. Here, we describe a 79-year-...

primary hepatic lymphoma (phl) is rare and possibly associated with viral hepatitis and autoimmune diseases. scleroderma could exceptionally be complicated by lymphoma. we describe phl occurring in a 52-year-old female suffering scleroderma for eight years, with no history of cytotoxic or high-dose glucocorticoid therapy. ct scan, performed to work-up abdominal discomfort, constipation, and ele...