In this work, a fibrous bed bioreactor with high specific surface area and good adsorption efficacy for S. cerevisiae cells was used as the immobilization matrix in the production of ethanol. In batch fermentation, an optimal ethanol concentration of 91.36 g/l and productivity of 4.57 g l(-1) h(-1) were obtained at an initial sugar concentration of 200 g/l. The ethanol productivity achieved by ...

In vitro fabrication of functional vascularized three-dimensional tissues has been a long-standing objective in the field of tissue engineering. Here we report a technique to engineer cardiac tissues with perfusable blood vessels in vitro. Using resected tissue with a connectable artery and vein as a vascular bed, we overlay triple-layer cardiac cell sheets produced from coculture with endothel...

Propylene glycol is discharged to the surface and underground waters and vicinity soils via industrial wastewater effluents, posing many health and environmental risks. The main goal of this study was to remove propylene glycol from synthetic wastewater in a fixed bed activated sludge reactor. To observe the effects of organic loading on bioreactor performance, the organic loading was increased...

Hydrodynamics has a strong influence on substrate elimination capacity in trickle-bed bioreactors (TBB). The present study reports the influence of liquid mass flow rate and bed void fraction on the TBB liquid residence time distribution (RTD), gas-liquid pressure drop, liquid hold-up, and biofilm wetting efficiency. Most RTD are well represented by a dispersion model. It is also shown that the...

−A packed bed external loop airlift bioreactor (PBELAB) was proposed as an alternative treatment system for wastewater containing ammonia and nitrate compounds. The 60L PBELAB consisted of aeration and non-aeration zones, both of which were packed with plastic bioballs to enhance the surface area for the attachment of bacteria. The system was able to achieve complete removal of all nitrogen com...

The paper deals with a distributed parameter system related to the socalled fixed-bed bioreactor. The original nonlinear partial differential system is linearized around the steady state. We find that the linearized system is not exactly controllable but it is approximatively controllable when certain algebraic equations hold. We apply frequency-domain methods (transfer function analysis) to co...

On-site biological treatment has been used for groundwater cleanup from industrial and agricultural chemicals. The pump-and-treat efficiency is controlled by retardation of contaminants by sorption onto the saturated subsurface solids and by the presence of non-aqueous-phase liquids in the aquifer. On-site bioreactors have been widely used for treatment of contaminants such as petroleum hydroca...

Solid-state fermentation requires the development of more efficient cultivation systems for its industrial application. The objective this work was to evaluate effect aeration regime on production biomass and several lignocellulolytic enzymes (laccase, manganese peroxidase, endoxylanase, β-glucosidase, total cellulases) by Trametes versicolor in a novel fixed-bed solid-state pilot-scale bioreac...

A method for formalization and analytical determination of the kinetic parameters of continuous alcohol fermentation in a reactor and in a cascade of reactors with ideal mixing was discussed in the present work. A fluidized bed bioreactor with immobilized yeast with elucidated structure of the flows was used. The method of formalization of the process kinetics involved two steps – determination...