Recent evidence suggests that pneumonitis induced by many important human viral pathogens may result from exuberant generation of reactive species by inflammatory cells in response to infection. This review summarizes current evidence from animal model studies regarding the beneficial (antiviral) and harmful (tissue-damaging) effects of reactive species for the host.

This review offers an overview of the influence of reactive species produced during exercise and their effect on exercise adaptation. Reactive species and free radicals are unstable molecules that oxidize other molecules in order to become stable. Although they play important roles in our body, they can also lead to oxidative stress impairing diverse cellular functions. During exercise, reactiv...

Cite this article: Oliveira AS, Martinez-de-Oliveira J, Palmeira-de-Oliveira R, Palmeira-de-Oliveira A, et al. (2017) Antifungal Activity of Antidepressant Sertraline against Candida Species In vitro: A Potential Beneficial Association with Fluconazole. Med J Obstet Gynecol 5(1): 1095. *Corresponding authors Ana Sofia Oliveira, CICS-UBI, Health Sciences Research Center, Faculty of Health Scienc...

There is an increasing recognition that patterns in species diversity cannot be understood without reference to nonequilibrial or unstable dynamics. Recently, through a realistic ecological model that involves dispersal, we have addressed the positive role of noise in promoting species coexistence [Phys. Rev. Lett. 94, 038102 (2005)]. Here we present a physical theory to account for the main sc...

Hypercholesterolemia drives the development of cardiovascular disease, the leading cause of mortality in western society. Supplementation with probiotics that interfere with cholesterol metabolism may provide a contribution to disease prevention. Lactobacillus plantarum CUL66 (NCIMB 30280) has been assessed in vitro for its ability to impact cholesterol absorption. L. plantarum CUL66 tested pos...

A well-established rat model of diet-induced metabolic syndrome was used to evaluate the effects of the oral administration of spores or cells of HU16, a carotenoid-producing strain of Bacillus indicus. Symptoms of metabolic syndrome were induced in 90-day old, male Sprague-Dawley rats maintained for eight weeks on a high-fat diet, as previously reported. Parallel groups of animals under the sa...

Nematodes are microscopic but complex unsegmented roundworms that are anatomically differentiated for feeding, digestion, locomotion, and reproduction. These small animals occur worldwide in all environments. Most species are beneficial to agriculture; they make important contributions to organic matter decomposition and are important members of the soil food chain. However, some species are pa...

Probiotics influence the immune system, both at the local and systemic level. Recent findings suggest the relation between microbiota and the immune system alters with age. Our objective was to address direct effects of six bacterial strains on immune cells from young and aged mice: Lactobacillus plantarum WCFS1, Lactobacillus casei BL23, Lactococcus lactis MG1363, Bifidobacterium breve ATCC157...

During the last years, the application of probiotics in gynaecological clinical practice has gained increasing relevance regarding therapy and prevention. This trend has also provoked the need for having tailored pharmaceutical preparations containing powerful microbial strains with defined properties. For the development of such preparations, several factors and criteria have to be considered,...