adrenocortical carcinoma (acc) is a rare tumor and usually a fatal disease which can develop at any age in either sex. differential diagnosis between malignant and benign adrenal mass is not easy which leads to significant clinical challenge for optimal treatment. here we report a 22-year-old woman diagnosed with primary hyper aldostronism initially but disease relapsed during six months and ma...

Results 32 children were included in the review with the diagnoses of Benign Joint Hypermobility Syndrome (BJHS), juvenile idiopathic arthritis (JIA), Juvenile Dermatomyositis (JDM) and Chronic Pain Syndrome (CPS). The mean follow up was 6 months of which 80% had maintained or increased their muscle strength since discharge. There was 100% school attendance and return to sport and 25% were doin...

Acute cerebellar syndrome can be caused by high doses of cytarabine, but it has not been described in patients with acute lymphoblastic leukemia (ALL) who received hyper-CVAD chemotherapy. Herein, we report two cases with histories of positive Philadelphia chromosome B-cell ALL who developed acute cerebellar syndrome after the exposure to relatively low doses of cytarabine in the second cycle o...

Here we present the case of a 27-year-old woman with benign joint hypermobility (BJHS) syndrome who developed keratectasia after laser in situ keratomileusis (LASIK) in both eyes. Both eyes had identical low Randleman risk factor scores. To our knowledge, this is the first report of such a complication in a patient with BJHS. It highlights our incomplete knowledge of the risk factors for kerate...

Introduction Chronic Musculoskeletal Pain (MSP) in children can be due to various non-inflammatory conditions, such as the benign joint hypermobility syndrome (BJHS) or idiopathic MSP (IMSP). MSP heavily influences patient’s quality of life and is often misdiagnosed or included in the vast category of unspecific MSP. A careful differential diagnosis and knowledge of possible risk factors are ne...

Background/introduction Magnetic resonance guided focused ultrasound surgery (MRgFUS) of the musculoskeletal system achieved significant results in the treatment of painful bone metastases, and recently showed promise for benign bone lesions (e.g. osteoid osteoma) and osteoarthritis (e.g. facet joint syndrome and knee osteoarthritis). MRgFUS works on the main basis of pain relief and tumor cont...

Three cases of gonorrhoea with pyrexia and lesions of the skin and joints (benign gonococcaemia) seen in one hospital group in 1969 within four months of one another are described. All three patients improved rapidly with penicillin therapy. This syndrome is commoner than is usually thought. It must therefore be borne in mind when a diagnosis is in doubt in a patient with unusual skin lesions a...

The hyperimmunoglobulinemia D and periodic fever (hyper-IgD) syndrome is typified by recurrent febrile attacks with abdominal distress, joint involvement (arthralgias/arthritis), headache, skin lesions, and an elevated serum IgD level (> 100 U/mL). This familial disorder has been diagnosed in 59 patients, mainly from Europe. The pathogenesis of this febrile disorder is unknown, but attacks are ...