نتایج جستجو برای: benzoxazines
تعداد نتایج: 156 فیلتر نتایج به سال:
A novel type of phosphazene containing an additive that acts both as a catalyst and flame retardant for benzoxazine binders is presented in this study. The synthesis derivative hexachlorocyclotriphosphazene (HCP) meta-toluidine was carried out the medium latter, which made it possible to achieve complete substitution chlorine atoms initial HCP. Thermal flammability characteristics modified comp...
Elevated activity of methionyl-tRNA synthetase (MRS) in many cancers renders it a possible drug target in this disease area, as well as in a series of parasitic diseases. In the present work, we report the synthesis and in vitro screening of a library of 1,3-oxazines, benzoxazines and quinoline scaffolds against human MRS. Among the compounds tested, 2-(2-butyl-4-chloro-1-(4-phenoxybenzyl)-1H-i...
Many pathogenic bacteria utilize two-component systems consisting of a histidine protein kinase (HPK) and a response regulator (RR) for signal transduction. During the search for novel inhibitors, several chemical series, including benzoxazines, benzimidazoles, bis-phenols, cyclohexenes, trityls, and salicylanilides, were identified that inhibited the purified HPK-RR pairs KinA-Spo0F and NRII-N...
Amines as additives in benzoxazines are known to beneficially affect the polymerization temperature and furthermore allow for partially reversible reaction steps yielding however a non-dynamic polybenzoxazine network. This contribution proves that behavior of two-component polymer polyetheramine Jeffamine® ED-600 bisphenol-A-based benzoxazine features stress-relaxation reprocessability usually ...
Eighteen new fused heterocyclic compounds of benzazoles and benzoxazines were investigated for induction and inhibition of apoptosis on tumor cells (L5718, mouse lymphoma cell line containing the human mdr-1 gene). For evaluation of apoptosis, the cells were stained with FITC-labelled Annexin-V and propidium iodide and the results were analysed by flow cytometry. Nine of these substances were a...
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