Ceftaroline is a new cephalosporin with bactericidal activity against methicillin-resistant S. aureus (MRSA) as well as gram-negative pathogens. Variations of in vitro test conditions were found to affect ceftaroline activity, with 5% NaCl inhibiting growth and/or reducing the minimum inhibitory concentrations (MICs) for E. coli, K. pneumoniae, M. catarrhalis, H. influenzae, and streptococci, w...

This study evaluated the inhibitory activity of copaiba oil (Copaifera officinalis against the cariogenic microorganism, Streptococcus mutans. For such purpose, a minimum inhibition concentration test of copaiba oil against S. mutans was performed, using the serial dilution in broth technique, with a negative control, a positive control (0.12% chlorhexidine) and a 10% copaíba oil solution as a ...

Background: Metal oxide nanoparticles (NPs) have shown promising efficacy for combating bacterial resistance due to their antibacterial properties. This research investigated the effect of zinc NPs (ZnO-NPs) on activity conventional antibiotics including ciprofloxacin (CIP), cefotaxime (CTX), and colistin (CST) against multidrug-resistant Acinetobacter isolates. Methods: The disc diffusion meth...

The activity of cefoperazone, a new broad-spectrum cephalosporin, was tested in vitro against 670 clinical isolates of gram-negative bacilli and gram-positive cocci. With the exception of Enterobacter spp., it inhibited the majority of all organisms tested at a concentration of 6.25 microgram/ml. Of particular interest is its good activity against Pseudomonas aeruginosa isolates which are usual...

Methicillin-resistant Staphylococcus aureus (MRSA) infection is a global health problem that needs to be answered by developing synthetic or natural antibacterial overcome the problem. The honey pineapple peel contains potentially compounds such as bromelain and flavonoid. This study aims determine activity of extract (Ananas comosus [L] Merr.) against MRSA. design this was true experimental wi...

Background and purpose: The status of medicinal plants in Iranian traditional medicine and rich existence of herbal sources, on one hand, and current problems in curing infections, on the other hand, are the factors to study medicinal plants more accurately. Tarragon (Artemisia dracunculus L.) is a herbaceous plant from Asteraceae family, available in planted and farming forms in Iran. This stu...

Multidrug-resistant bacteria continue to pose the greatest threat public health. Metallic nanoparticles are one of more promising strategies for combating antibiotic resistance. This research aims determine effect gold and silver gold-silver alloy as antibacterial agents. On other hand, biogenic synthesized using Ziziphus spina-christi leaf extract preparation treatment multidrug-resistant were...

gentamicin is a bactericidal aminoglycoside antibiotic, it inhibits the protein synthesis. gentamicin is active against the majority of aerobic gram-negative bacilli such as pseudomonas, klebsiella and escherichia coli. the gentamicin doses are 3 mg/kg once-daily for preterm newborns < 35 weeks of gestation and 4 mg/kg once-daily for newborns > 35 weeks of gestation. the monitoring of gentamici...

BACKGROUND Multidrug resistance is a worrying cause of treatment failure in bacterial infections. The search of bioactive constituents from medicinal plants against multidrug resistant (MDR) bacteria has significantly evolved in the two last decades. In the present study, twenty-two compounds (three terpenoids, eleven phenolics and eight alkaloids) isolated from three Cameroonian medicinal plan...

recreational waters should be considered as risks for enterococcal infections in regions with high utilization and long exposure periods. the aim of this study was to investigate the resistance of enterococci to selected antibiotics and some heavy metals [pb+2, fe+2, zn+2 and cr+2]. a total of 75 enterococcal isolates was obtained from 54 bathing and fishing water samples from 9 bathing and fis...