نتایج جستجو برای: bernard soulier syndrome

تعداد نتایج: 627301  

2017
Arshi Naz Muhammad Younus Jamal Samina Amanat Ikram Din Ujjan Akber Najmuddin Humayun Patel Fazle Raziq Nisar Ahmed Ayisha Imran Tahir Sultan Shamsi

BACKGROUND Autosomal recessive bleeding disorders (ARBDs) include deficiencies of clotting factors I, II, V, VII, X, XI, XIII, vitamin K dependent clotting factors, combined factor V & VIII, Von Willebrand Disease (vWD) type 3, Glanzmann's thrombasthenia (GT) and Bernard-Soulier syndrome. Patients with primary bleeding disorders from all the major provincial capitals of Pakistan were screened f...

Journal: :Blood 2013
Mario Cazzola

given the knownGPIb/IX/V pathobiology in Bernard-Soulier syndrome and that Mx1-C1 mice have characteristics similar to that syndrome. Clearly, glycosylation of other surface receptors and perhaps other proteins may contribute to the observed defect in thrombopoiesis and may have been missed. The findings of Kudo et al set the stage for further research on the mechanism by which GPIba O-glycosyl...

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