The inclusion of small amounts copper is often reported to enhance the mechanical and biointegrative performance bioceramics towards tissue engineering applications. In this work, 3D scaffolds were additively manufactured by robocasting precipitation derived doped diopside. Compositions chosen in which magnesium sites diopside substituted up 3 at.%. Microstructure, performance, bioactivity, bio...

Abstract Exosomes have attracted increasing attention in tissue regeneration and repair due to their roles intercellular communication. Developing a customized delivery system is key exosome-based regenerative therapeutics. Bioceramics play an important role the immunomodulation of macrophages. Here, three-dimensional (3D) printing was applied construct porous scaffolds with β-tricalcium phosph...

Addition of copper in biomaterials is currently investigated because it expected to enhance the biological properties bone graft substitutes. Copper-doped hydroxyapatite (CuHA) ceramics were prepared by high temperature solid-state reaction sintering between HA and CuO powder mixtures. The occurred from 950 °C copper-doped apatites obtained up 5.3 wt% copper. For higher content, presence second...

Porous functional graded ceramics (porous FGCs) offer immense potential to overcome the low mechanical strengths of homogeneously porous bioceramics used as bone grafts. The tailored manipulation pore structure including interfaces in these materials is particular interest locally control microstructural and properties, well biological response implant. In this work, FGCs with integrated interf...

Objective (s): Silicate bioceramics containing Zn and Ca like hardystonite (Hr) with chemical formula Ca2ZnSi2O7 has attracted the attention of researchers in biomedical field due to its remarkable biological and mechanical properties. The new generation of bioceramics can applied in bone tissue engineering to substitute with infected bone. However, these zirconium-silicate bioceramics have pro...