A hypothesis is presented that electronic and vibrational resonant energy states are important in biochemical reactions due to their coupling to hydrogen transfer reactions. The hypothesis is based upon (1) the involvement of hydrogen in most biochemical reactions, (2) the unique abiity of hydrogen to act as an energy trap for resonant energy and (3) demonstrations of the coupling of resonant e...

Purpose: The aim of this study is to evaluate the diagnosis characteristics, clinic findings, phenotypical and genotypical features children with GM2 gangliosidoses.
 Materials Methods: file records 14 patients diagnosed gangliosidoses in our were retrospectively reviewed. was confirmed by determining levels serum total hexosaminidase β-hexosaminidase activity genetic analysis. 
 Resu...

Many protein and mRNA species occur at low molecular counts within cells, and hence are subject to large stochastic fluctuations in copy numbers over time. Development of computationally tractable frameworks for modelling stochastic fluctuations in population counts is essential to understand how noise at the cellular level affects biological function and phenotype. We show that stochastic hybr...